Results 41 to 50 of about 15,377,418 (177)

Etoposide as Salvage Therapy for Cytokine Storm due to COVID-19

, 2020
Coronavirus disease 2019 (COVID-19) has resulted in significant morbidity and mortality because of a lack of effective therapies. Therapeutic strategies under investigation target the overactive cytokine response with anti-cytokine or immunomodulators ...
Bromberg, Michael, Criner, Gerard J., 0000-0002-1828-6524, 0000-0003-2402-1351, Caricchio, Roberto, Patel, Maulin, Sacher, Daniel, Desai, Parag, Chandar, Ashwin, Dominguez Castillo, Eduardo, 0000-0002-1379-1118   +10 more
core   +1 more source

Relação entre os Sinais de Strain do Ventrículo Direito no Eletrocardiograma e Níveis de Biomarcadores Associados à Gravidade da Pneumonia por COVID-19

Arquivos Brasileiros de Cardiologia, 2021
Resumo Fundamento A nova doença por coronavírus (COVID-19) pode levar a uma enfermidade grave e causar a morte. Sabe-se que a COVID-19 afeta o sistema cardiovascular.
Veli Polat, Evin Bozcali, Kadriye Kart Yasar, Hayat Kumbasar Karaosmanoglu, Ibrahim Faruk Akturk   +4 more
doaj   +2 more sources

Prevalence of high‐risk plasma p‐tau217 levels and 5‐year transition of risk status in 70‐year‐olds

Alzheimer's &Dementia, Volume 22, Issue 6, June 2026.
Abstract INTRODUCTION High‐risk plasma p‐tau217 levels predict amyloid‐β pathology in Alzheimer's disease, but little is known about the prevalence and temporal dynamics in the general population. METHODS Participants from the Gothenburg H70 Birth Cohort Study in Sweden were examined (n = 1157) and re‐examined after 5–7 years (n = 771).
Anna Dittrich, Burak Arslan, Tobias Skillbäck, Lina Rydén, Hlin Kvartsberg, Johan Gobom, Kaj Blennow, Henrik Zetterberg, Silke Kern, Ingmar Skoog   +9 more
wiley   +1 more source

Preliminary predictive criteria for COVID-19 cytokine storm

, 2020
Objectives: To develop predictive criteria for COVID-19-associated cytokine storm (CS), a severe hyperimmune response that results in organ damage in some patients infected with COVID-19.
Bromberg, Michael, 0000-0003-4737-8003, Criner, Gerard J., Zhang, Xinyan, Gallucci, Marcello, Dass, Chandra, Caricchio, Roberto, Gallucci, Stefania, Fleece, David, 0000-0002-1379-1118   +9 more
core   +1 more source

AVANÇOS NO ENTENDIMENTO DA PATOGENIA DA COVID-19: UMA REVISÃO

Arquivos de Ciências da Saúde da UNIPAR
Introdução: O SARS-CoV-2, causador da pandemia por Doença por Coronavirus 2019 (COVID-19) gerou desafios à saúde pública, principalmente pelo conhecimento escasso de sua patogênese, e de estratégias terapêuticas e preventivas eficazes.
Gilcele Campos Martin Berber, Renata Dezengrini Slhessarenko   +1 more
doaj   +1 more source

FATORES ASSOCIADOS À INFECÇÃO EM GRUPOS COM CONDIÇÕES CLÍNICAS DE RISCO PARA COMPLICAÇÕES POR COVID-19

REME: Revista Mineira de Enfermagem, 2021
RESUMO Objetivo: analisar fatores de risco associados à infecção por COVID-19 em grupos com condições clínicas de risco para desenvolvimento de complicações pela doença.
Fernando José Guedes da Silva Júnior, Jaqueline Carvalho e Silva Sales, Chrystiany Plácido de Brito Vieira, Ana Paula Cardoso Costa, Luana Ruth Braga Campos, Priscilla Ingrid Gomes Miranda, Andreia Alves de Sena Silva, Karoline Alencar Rodrigues   +7 more
doaj  

Potential vectors of Leishmaniases in the Environmental Protection Area and Tinguá Federal Biological Reserve, Municipality of Nova Iguaçu, Rio de Janeiro, Brazil

Medical and Veterinary Entomology, Volume 40, Issue 2, Page 246-259, June 2026.
This study was to describe the composition of sand fly fauna, detect potential vectors of Leishmania spp. in the Tinguá district, an ATL endemic, Rio de Janeiro, Brazil. Seven species of vectorial importance in the epidemiological cycle of leishmaniasis was observed: Nyssomyia intermedia, Migonemyia migonei, Pintomyia fischeri, Psychodopygus hirsutus ...
Antônio L. F. Santana, Alfredo C. R. Azevedo, Margarete M. S. Afonso, Bruno M. Carvalho, Vanessa R. Vieira, Simone M. Costa, Júlia S. Silva, Thais A. Pereira, Daniela P. Pereira, Maurício L. Vilela   +9 more
wiley   +1 more source

Vaccination Coverage and Factors Associated With Incomplete Vaccination Schedules in Children Under 5 in a Peripheral Area of the Federal District of Brazil

Public Health Nursing, Volume 43, Issue 3, Page 543-553, May/June 2026.
ABSTRACT Objective To estimate vaccination coverage (VC) and analyze the factors associated with the incomplete vaccination schedule (IVS) in children under 5 years of age in two Basic Health Units in the Federal District of Brazil. Design A cross‐sectional study.
Ivea Rayane Mendes Nicacio Viana, Henry Maia Peixoto   +1 more
wiley   +1 more source

Fluvoxamine for Outpatient Treatment of COVID-19: A Decentralized, Placebo-controlled, Randomized, Platform Clinical Trial

, 2022
BACKGROUND: The effectiveness of fluvoxamine to shorten symptom duration or prevent hospitalization among outpatients in the US with mild to moderate symptomatic coronavirus disease 2019 (COVID-19) is unclear. DESIGN: ACTIV-6 is an ongoing, decentralized,
Boulware, David R., Stewart, Thomas G., Adam, Stacey J., Castro, Mario, Lindsell, Christopher J., Hanna, George, Ruiz-Unger, Juan, Singh, Upinder, Gentile|, Hernandez, Adrian F., Wilder, Rhonda, Thicklin, Florence, McTigue, Kathleen, Ginde, Adit A., Bramante, Carolyn, DeLong, Allison, Felker, G. Michael, Dolor, Rowena J., McCarthy, Matthew W., Wilson, Sybil, Sulkowski, Mark, Collins, Sean, Dunsmore, Sarah E., Jayaweera, Dushyantha, Remaly, April, Gentile, Nina, Naggie, Susanna, Shenkman, Elizabeth   +27 more
core   +1 more source

Persistent and Emerging High‐Risk Clusters of Leprosy Detection in Brazil: A Nationwide Spatiotemporal Analysis, 2001–2023

Tropical Medicine &International Health, Volume 31, Issue 4, Page 532-546, April 2026.
ABSTRACT Background Brazil accounts for a substantial share of the global leprosy burden, with persistent high‐risk areas and marked spatial inequalities in case detection. Identifying spatiotemporal clusters of transmission is crucial for targeting surveillance and control efforts.
Anderson Fuentes Ferreira, Jorg Heukelbach, Eliana Amorim de Souza, Carmelita Ribeiro Filha Coriolano, Elaine Silva Nascimento Andrade, Aymée Medeiros da Rocha, José Alexandre Menezes da Silva, Carlos Dornels Freire de Souza, Juliana Maria Cavalcante Ribeiro Ramos, Alberto Novaes Ramos Jr   +9 more
wiley   +1 more source