Results 1 to 10 of about 65,904 (150)

Ozonated Oil for Rheumatic Diseases [PDF]

Advanced Pharmaceutical Bulletin
Jozélio Freire de Carvalho, Ana Tereza Amoedo Martinez   +1 more
doaj   +2 more sources

Identification of Neurotransmission and Synaptic Biological Processes Disrupted in Autism Spectrum Disorder Using Interaction Networks and Community Detection Analysis

Biomedicines, 2023
Autism Spectrum Disorder (ASD) is a neurodevelopmental disorder characterized by communication deficits and repetitive behavioral patterns. Hundreds of candidate genes have been implicated in ASD, including neurotransmission and synaptic (NS) genes ...
Joana Vilela, Hugo Martiniano, Ana Rita Marques, João Xavier Santos, Muhammad Asif, Célia Rasga, Guiomar Oliveira, Astrid Moura Vicente   +7 more
doaj   +1 more source

Gene Variants Involved in Nonsense-Mediated mRNA Decay Suggest a Role in Autism Spectrum Disorder

Biomedicines, 2022
Autism Spectrum Disorder (ASD) is a heterogeneous neurodevelopmental condition with unclear etiology. Many genes have been associated with ASD risk, but the underlying mechanisms are still poorly understood.
Ana Rita Marques, João Xavier Santos, Hugo Martiniano, Joana Vilela, Célia Rasga, Luísa Romão, Astrid Moura Vicente   +6 more
doaj   +1 more source

Gout in a patient with Paget’s disease [PDF]

Beyond Rheumatology, 2022
Objective: We aimed at describing a patient with Paget’s Disease (PD) who developed gout. Case Presentation: A 65-year-old male patient with a long history of right hip pain, podagra, and knees with gait impairment and laboratory tests showing alkaline ...
J. de Carvalho, C. Figueiredo
doaj   +1 more source

Performance comparison of different classification algorithms applied to the diagnosis of familial hypercholesterolemia in paediatric subjects

Scientific Reports, 2022
Familial Hypercholesterolemia (FH) is an inherited disorder of lipid metabolism, characterized by increased low density lipoprotein cholesterol (LDLc) levels.
João Albuquerque, Ana Margarida Medeiros, Ana Catarina Alves, Mafalda Bourbon, Marília Antunes   +4 more
doaj   +1 more source

Characterization of Two Variants at Met 1 of the Human LDLR Gene Encoding the Same Amino Acid but Causing Different Functional Phenotypes

Biomedicines, 2021
Familial hypercholesterolemia (FH) is the most common genetic disorder of lipid metabolism, characterized by increased levels of total and LDL plasma cholesterol, which leads to premature atherosclerosis and coronary heart disease.
Rafael Graça, Rafael Fernandes, Ana Catarina Alves, Juliane Menezes, Luísa Romão, Mafalda Bourbon   +5 more
doaj   +1 more source

Disease similarity network analysis of Autism Spectrum Disorder and comorbid brain disorders

Frontiers in Molecular Neuroscience, 2022
Autism Spectrum Disorder (ASD) is a neurodevelopmental disorder with heterogeneous clinical presentation, variable severity, and multiple comorbidities. A complex underlying genetic architecture matches the clinical heterogeneity, and evidence indicates ...
Joana Vilela, Joana Vilela, Hugo Martiniano, Hugo Martiniano, Ana Rita Marques, Ana Rita Marques, João Xavier Santos, João Xavier Santos, Célia Rasga, Célia Rasga, Guiomar Oliveira, Guiomar Oliveira, Astrid Moura Vicente, Astrid Moura Vicente   +13 more
doaj   +1 more source

Are we PREPAREd? Concerning the “PREemptive Pharmacogenomics Testing for Preventing Adverse Drug Reactions (PREPARE) Study”

Acta Médica Portuguesa, 2023
N/a.
Ana de Carmo Campos, Maria Luís Cardoso, Astrid Vicente   +2 more
doaj   +1 more source

Helicobacter pylori eradication effects on rheumatic diseases: a systematic review [PDF]

Microbiota in Health and Disease, 2023
Objective: Helicobacter pylori (HP) eradication treats peptic ulcers, gastric lymphoma, or adenocarcinoma. Although, there are effects on the rheumatic disease activity.
J. Freire de Carvalho, V. Figueiredo
doaj   +1 more source

Perfil dos ensaios clínicos submetidos para apreciação ética da Comissão Nacional de Ética em Pesquisa entre 2015 a 2019

Brazilian Journal of Forensic Sciences, Medical Law and Bioethics, 2021
O objetivo deste trabalho é caracterizar os ensaios clínicos submetidos para análise ética da Conep, registrados na base de dados da Plataforma Brasil de 2015 a 2019, e comparar os ensaios clínicos nacionais e internacionais.
Ludmila Naud
doaj   +1 more source