Results 1 to 10 of about 134 (76)

Cryptococcus extracellular vesicles properties and their use as vaccine platforms

Journal of Extracellular Vesicles, Volume 10, Issue 10, August 2021., 2021
Abstract Whereas extracellular vesicle (EV) research has become commonplace in different biomedical fields, this field of research is still in its infancy in mycology. Here we provide a robust set of data regarding the structural and compositional aspects of EVs isolated from the fungal pathogenic species Cryptococcus neoformans, C. deneoformans and C.
Juliana Rizzo, Sarah Sze Wah Wong, Anastasia D. Gazi, Frédérique Moyrand, Thibault Chaze, Pierre‐Henri Commere, Sophie Novault, Mariette Matondo, Gérard Péhau‐Arnaudet, Flavia C. G. Reis, Matthijn Vos, Lysangela R. Alves, Robin C. May, Leonardo Nimrichter, Marcio L. Rodrigues, Vishukumar Aimanianda, Guilhem Janbon   +16 more
wiley   +1 more source

Immunopathogenesis of the feline atopic syndrome

Veterinary Dermatology, Volume 32, Issue 1, Page 13-e4, February 2021., 2021
Résumé Contexte Les maladies félines supposées d’origine allergique avec des phénotypes cliniques semblables, peuvent avoir de nombreuses pathogénies différentes sous jacentes. Le phénotype clinque, l’étiologie précise et l’immunopathogénie sous jacente doivent tous être considérés si des avancées veulent être faites dans ces domaines négligés de la ...
Richard Halliwell, Frane Banovic, Ralf S. Mueller, Thierry Olivry   +3 more
wiley   +1 more source

Assessment of the In Vitro Antischistosomal Activities of the Extracts and Compounds from Solidago Microglossa DC (Asteraceae) and Aristolochia Cymbifera Mart. & Zucc. (Aristolochiaceae)

Evidence-Based Complementary and Alternative Medicine, Volume 2020, Issue 1, 2020., 2020
Schistosomiasis, caused by helminth flatworms of the genus Schistosoma, is a neglected tropical disease that afflicts over 230 million people worldwide. Currently, treatment is achieved with only one drug, praziquantel (PZQ). In this regard, the roots of Solidago microglossa (Asteraceae) and Aristolochia cymbifera (Aristolochiaceae) are popularly used ...
Poliana da Silva Costa, Ohana Oliveira Zuza da Silva, Danilo de Souza Costa, Lara Aparecida de Oliveira Silva, Priscila de Faria Pinto, Marcos Paulo Nascimento da Silva, Josué de Moraes, Ademar A. Da Silva Filho, Adolfo Andrade-Cetto   +8 more
wiley   +1 more source

In Vitro Schistosomicidal Activity of the Alkaloid‐Rich Fraction from Ruta graveolens L. (Rutaceae) and Its Characterization by UPLC‐QTOF‐MS

Evidence-Based Complementary and Alternative Medicine, Volume 2019, Issue 1, 2019., 2019
Schistosomiasis is a neglected tropical disease that affects million people worldwide, mostly in developing countries. Ruta graveolens (Rutaceae) is a plant used in folk medicine to treat several diseases, including parasitic infections. In this study, we reported the in vitro schistosomicidal activity of the R.
Lara Soares Aleixo de Carvalho, Lucas Sales Queiroz, Ismael José Alves Junior, Ayla das Chagas Almeida, Elaine Soares Coimbra, Priscila de Faria Pinto, Marcos Paulo Nascimento da Silva, Josué De Moraes, Ademar A. Da Silva Filho, Marco Leonti   +9 more
wiley   +1 more source

TGF‐β Polymorphisms Are a Risk Factor for Chagas Disease

Disease Markers, Volume 2018, Issue 1, 2018., 2018
Transforming growth factor β1 (TGF‐β1) is an important mediator in Chagas disease. Furthermore, patients with higher TGF‐β1 serum levels show a worse clinical outcome. Gene polymorphism may account for differences in cytokine production during infectious diseases.
Roberto Rodrigues Ferreira, Fabiana da Silva Madeira, Gabriel Farias Alves, Mayara da Costa Chambela, Eduardo de Oliveira Vaz Curvo, Aline dos Santos Moreira, Renata Almeida de Sá, Leila Mendonça-Lima, Pedro Hernan Cabello, Sabine Bailly, Jean-Jacques Feige, Tania Cremonini Araujo-Jorge, Roberto Magalhães Saraiva, Mariana Caldas Waghabi, Paul Ashwood   +14 more
wiley   +1 more source

Mutagenic and Cytotoxicity LQB 123 Profile: Safety and Tripanocidal Effect of a Phenyl‐t‐Butylnitrone Derivative

BioMed Research International, Volume 2017, Issue 1, 2017., 2017
The therapeutic options for Chagas disease are limited and its treatment presents a number of drawbacks including toxicity, drug resistance, and insufficient effectiveness against the chronic stage of the disease. Therefore, new therapeutical options are mandatory.
Mauricio Peixoto Cupello, Francis Monique Saraiva, Pedro Ippolito, Andréia da Silva Fernandes, Rubem Figueiredo Sadoko Menna-Barreto, Debora de Sousa dos Santos Costa, Jessica Isis Oliveira Paula, Paulo Roberto Ribeiro Costa, Natália Pereira Nogueira, Israel Felzenswalb, Ayres Guimarães Dias, Marcia Cristina Paes, Peter Fu   +12 more
wiley   +1 more source

Flavonoids and Sesquiterpene Lactones from Artemisia absinthium and Tanacetum parthenium against Schistosoma mansoni Worms

Evidence-Based Complementary and Alternative Medicine, Volume 2016, Issue 1, 2016., 2016
Human schistosomiasis, caused by trematode worms of the genus Schistosoma, is one of the most significant neglected tropical diseases, affecting more than 200 million individuals worldwide and praziquantel is the only available drug to treat this disease. Artemisia absinthium L. and Tanacetum parthenium L.
Luísa Maria Silveira de Almeida, Lara Soares Aleixo de Carvalho, Matheus Coutinho Gazolla, Pedro Luiz Silva Pinto, Marcos Paulo Nascimento da Silva, Josué de Moraes, Ademar A. Da Silva Filho, Andrea Maxia   +7 more
wiley   +1 more source

The aorta at the center. [PDF]

J Vasc Bras, 2023
Brito-Queiroz A, Mulatti GC, Dos Santos VP.   +2 more
europepmc   +1 more source

Defibrillation Threshold in Patients with Chronic Chagas' Heart Disease: Are There Benefits or not Worth the Risk? [PDF]

Arq Bras Cardiol, 2022
Teixeira RA.
europepmc   +1 more source

Botulism in the Brazilian Amazon: a life-threatening disease in a neglected population. [PDF]

Arq Neuropsiquiatr, 2022
Oliveira LM, Gonçalves DB, Cabral LCR, Bernardino MRA, Feitoza PVS.   +4 more
europepmc   +1 more source