Results 201 to 210 of about 1,211,793 (274)

Recognizing and Mitigating Canine Stress in Human-Canine Interaction Research: Proposed Guidelines. [PDF]

Animals (Basel)
Sidel SB, Gandenberger J, Murphy K, Morris KN.   +3 more
europepmc   +1 more source

Implementing BMP‐7 Chemically Modified RNA for Bone Regeneration with 3D Printable Hyaluronic Acid‐Collagen Granular Gels

Advanced Healthcare Materials, EarlyView.
This study developed 3D‐printable THA‐Col microgels for delivering BMP‐7 cmRNA. The key result is that hMSCs transfected on the biomaterials showed BMP‐7 secretion levels comparable to pre‐transfected hMSCs, therefore introducing a cmRNA‐activated matrix to promote bone healing.
Daphne van der Heide, Claudia del Toro Runzer, Elena Della Bella, Christian Plank, Martijn van Griensven, Elizabeth Rosado Balmayor, Martin J. Stoddart, Matteo D'Este   +7 more
wiley   +1 more source

Enhancing the Pharmacokinetics of Aptamers: Targeting AXL In Vivo Using a Bottlebrush Polymer‐Conjugated Aptamer

Advanced Healthcare Materials, EarlyView.
A phosphodiester‐backboned bottlebrush polymer (pacDNA) engineered for aptamer delivery is presented. This design enhances aptamer stability, plasma pharmacokinetics, and target engagement in vivo. In AXL‐driven cancer models, pacDNA inhibits AXL signaling and reduces tumor growth, highlighting the promise of precision polymer scaffolds in aptamer ...
Tingyu Sun, Jiachen Lin, Chenyang Xue, Yuyan Wang, Peiru Chen, Yun Wei, Guobin Xu, Anais Sidonia, Chris Nenopoulos, Hossam Tashkandi, Caroline Shen, Allison Wang, Alex Wang, Ke Zhang   +13 more
wiley   +1 more source

Study on adolescents' attitudes and attachment toward companion animals: mitigating the negative effects of cultural estrangement on wellbeing. [PDF]

Front Psychol
Koyasu H, Ogasawara S, Kikusui T, Murai T, Nishida A, Nagasawa M.   +5 more
europepmc   +1 more source

Semiconducting Polymer Nanoparticles as Multimodal Agents for Optical and Magnetic Resonance Imaging

Advanced Healthcare Materials, EarlyView.
Semiconducting polymer nanoparticles (SPNs) exhibit many advantageous optical and biological properties. Multimodal SPN‐based contrast agents that integrate several imaging modalities yield a wealth of information through the use of different imaging mechanisms.
Faysal A. Farah, Yu Qin, Mark A. Green, James D. E. T. Wilton‐Ely   +3 more
wiley   +1 more source

The Vertebrate Breed Ontology: Toward Effective Breed Data Standardization. [PDF]

J Vet Intern Med
Mullen KR, Tammen I, Matentzoglu NA, Mather M, Balhoff JP, Esdaile E, Leroy G, Park CA, Rando HM, Saklou NT, Webb TL, Vasilevsky NA, Mungall CJ, Haendel MA, Nicholas FW, Toro S.   +15 more
europepmc   +1 more source

Aging on Chip: Harnessing the Potential of Microfluidic Technologies in Aging and Rejuvenation Research

Advanced Healthcare Materials, EarlyView.
This review highlights recent advances in microfluidic technologies for modeling human aging and age‐related diseases. It explores how organ‐on‐chip platforms improve physiological relevance, enable rejuvenation strategies, facilitate drug screening, detect senescent cells, and identify biomarkers.
Limor Zwi‐Dantsis, Vignesh Jayarajan, George M. Church, Roger D. Kamm, João Pedro de Magalhães, Emad Moeendarbary   +5 more
wiley   +1 more source

The Selection and Training of Shelter Dogs for Involvement in Canine-Assisted Interventions: What Are the Ethical Issues? [PDF]

Vet Sci
Contalbrigo L, Walsh EA, Meers LL, Benedetti D, De Santis M, Bassan E, Normando S.   +6 more
europepmc   +1 more source

Membrane Fusion‐Inspired Nanomaterials: Emerging Strategies for Infectious Disease and Cancer Diagnostics

Advanced Healthcare Materials, EarlyView.
Membrane fusion‐inspired nanomaterials offer transformative potential in diagnostics by mimicking natural fusion processes to achieve highly sensitive and specific detection of disease biomarkers. This review highlights recent advancements in nanomaterial functionalization strategies, signal amplification systems, and stimuli‐responsive fusion designs,
Sojeong Lee, Khulan Nyamzaya, Jueun Han, Yejin Song, Jihee Lee, Jung Hyun Jo, Seungmin Bang, Eun‐Kyung Lim, Seungjoo Haam, Eunjung Kim   +9 more
wiley   +1 more source

To Hunt or Patrol? Social Composition and Location Mediate Scent Marking Decisions of a Large Carnivore. [PDF]

Ecol Evol
Hansen KW, Jordan NR, Claase MJ, McNutt JW, Wilson A, Wilmers CC.   +5 more
europepmc   +1 more source