Results 91 to 100 of about 118,724 (306)
Advanced Science, EarlyView.Using iPSC‐derived motoneurons and postmortem tissue from FUS‐ALS patients, it is demonstrated that increased mitochondrial transcription leads to elevated cytosolic double‐stranded RNA (dsRNA) levels. This aberrant accumulation activates a RIG‐I–dependent innate immune response leading to neurodegeneration, which is amenable for FDA‐ and EMA‐approved ...
Marcel Naumann +26 more
wiley +1 more source
Multiple open wrist fractures and dislocation of the distal radioulnar joint from a dog bite injury
Radiology Case Reports, 2019 Dogs are commonly kept as household pets, but sometimes pet dogs bite people. We report the case of a 69-year-old man who was bitten by his pet pit bull terrier.
Annemarie Relyea-Chew, JD, MS +1 more
doaj +1 more source
Kajian Epidemiologi Dan Dampak Sosial Penyakit Rabies Terhadap Masyarakat Di Kabupaten Manggarai Periode 2001-2006 [PDF]
, 2009 The aims of this research are to know how about the epidemiology and social impact of rabies desease on society in Manggarai regency and to find the exact design for preventative and eliminate the rabies desease.This research was done during 8 (eight)
Angi, A. H. (Andrijanti) +2 more
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Advanced Science, EarlyView.This study demonstrates that Mn2⁺–tumor DNA complexes encapsulated in dendritic cell (DC)– derived immunogenic extracellular vesicles (EVDC@Mn‐DNA) act as a DC‐specific cGAS– STING activator. EVDC@Mn‐DNA treatment enhances intratumoral DC activation, improves tumor vascular function, promotes CD8⁺ T cell activity, and suppresses pancreatic tumor growth,
Xue Jiang +13 more
wiley +1 more source
Forecasting Dog Bite Incidents: An Autoregressive Integrated Moving Average Time Series Analysis
Preventive Medicine: Research & ReviewsIntroduction: This study, driven by the high incidence of dog bites in India and the fatality risk of rabies, utilised Autoregressive Integrated Moving Average (ARIMA) analysis to forecast dog bite trends in a metropolitan tertiary care hospital ...
Dinesh Asokan +4 more
doaj +1 more source
PD‐1 Inhibits CD4+ TRM‐Mediated cDC1 Mobilization via Suppressing JAML in Human NSCLC
Advanced Science, EarlyView.CD4+ tissue‐resident memory T cells (TRMs) in non‐small cell lung cancer recruit conventional type 1 dendritic cells via XCL1‐XCR1 signaling, orchestrating antitumor immunity. The costimulatory molecule JAML is essential for this process. PD‐1 blockade restores JAML expression and cDC1 mobilization, while JAML agonists synergize with anti‐PD‐1 therapy,
Zheyu Shao +16 more
wiley +1 more source
BMC Public Health, 2018 Background Human animal-bite injuries are a serious public health problem due to associated risk for rabies virus exposure. Animal-bite injuries especially dog bites are useful indicators for assessing the risk of rabies virus transmission and need for ...
Jeremiah Ngurimu Ngugi +3 more
doaj +1 more source
Recent Developments in Animal Law [PDF]
, 2005 This article focuses on recent developments in litigation and legislation involving the injury or death of animals. The article first discusses recent veterinary malpractice cases where the central issue was not related to damages.
Huss, Rebecca J.
core +1 more source