Results 111 to 120 of about 118,724 (306)
Advanced Science, EarlyView.This study identifies OCIAD2 as a critical regulator of cisplatin resistance in HNSCC. Mechanistically, OCIAD2 stabilizes integrin β1 through a direct physical interaction and facilitates its SNX17‐dependent endosomal recycling to lipid raft microdomains. Targeting OCIAD2 disrupts integrin β1 trafficking and significantly enhances cisplatin sensitivity,
Li Cui +9 more
wiley +1 more source
The Effect of the Dog Breed Ban on Bite Incidences and the Usage of Rabies Post-Exposure Prophylaxis on Fort Riley [PDF]
Master of Public HealthPublic Health Interdepartmental ProgramMichael B. CatesThis study evaluated the impact that the Banned Dog Breed Policy on Fort Riley military installation has had on the number of dog bite-related injuries seen in the emergency ...
Collins, Hayley
core
Advanced Science, EarlyView.We established patient‐derived SWN cell lines and orthotopic PDX models that recapitulate patient pain phenotypes, alongside a novel intravital DRG imaging platform to track macrophage infiltration and neuronal pain responses. Using these models, we define HMGB1–CCL2–IL‐6 signaling crosstalk driving pain and identify EGF signaling as a key regulator of
Zhenzhen Yin +17 more
wiley +1 more source
National Journal of Community Medicine, 2018 Introduction: Rabies, a zoonotic disease transmitted by bite of a rabid animal mostly due to dog bite. Rabies is deadly but can be prevented by post exposure prophylaxis with an effective vaccine available. Though 100% fatal disease, the victims are not
Satish K Wadde +3 more
doaj
Advanced Science, EarlyView.In pancreatic ductal adenocarcinoma (PDAC), insulin is associated with activation of PI3K/AKT–RAB3A signaling and enhanced secretion of TNFAIP8‐enriched exosomes from tumor cells. Uptake of these exosomes by fibroblasts is linked to TRIM21‐dependent STAT1 degradation and the emergence of myofibroblastic CAF–associated features, accompanied by increased
Zhenyu Li +15 more
wiley +1 more source
Advanced Science, EarlyView.This study reveals the genetic and molecular mechanisms controlling grain size homeostasis through fine‐tuning OsGRX8 self‐expression by two natural negative feedback loops functioning in redox‐dependent or ‐independent manners and identifies two self‐regulatory haplotypes (SRHs) for the subspecies differentiation in rice.
Xingxing Li +13 more
wiley +1 more source
Incidence rate of rabies vaccination delay after dog bite in Guilan province
Journal of Holistic Nursing and Midwifery, 2015 Introduction: Rabies vaccination after animal bite is the most important method for prevention of rabies. Delay in rabies vaccination increases the risk of rabies after animal bites.
Davoud Pourmarzi, Maryam Razi
doaj
Advanced Science, EarlyView.This study investigates how the internal structure of fiber‐reinforced ceramic composites affects their resistance to damage. By combining 3D X‐ray imaging with acoustic emission monitoring during mechanical testing, it reveals how silicon distribution influences crack formation.
Yang Chen +7 more
wiley +1 more source
Knowledge graph analysis of particles in Japanese [PDF]
, 2005 The theory of knowledge graphs is a structuralistic theory of language. Its ontology consists of eight types of binary relationships and four types of so-called frames. The relationships connect so-called tokens, that represent semantic units.
Hoede, C.
core +1 more source