Results 121 to 130 of about 234,807 (237)

Dog bites in the emergency department: a descriptive analysis

open access: yes, 2018
ObjectiveThe purpose of this study was to assess the pattern of adult dog bites presenting to a medium size Canadian city’s Emergency Departments.MethodsAll adult (≥16 years) patients presenting to Emergency Departments in our region during a 30-month ...
Alexander Morzycki   +2 more
core   +1 more source

Lactate‐Induced K370 Lactylation of STING Inhibits STING‐TBK1 Signaling and Dampens Anti‐Tumor Immunity

open access: yesAdvanced Science, EarlyView.
Lactate accumulation in glioblastoma drives lactylation of STING at lysine 370, a primate‐conserved residue. K370 lactylation weakens STING‐TBK1 binding, destabilizes STING, and disrupts ER‐to‐Golgi trafficking, blunting type I interferon signaling. LDHA inhibition reverses K370 lactylation and improves the antitumor efficacy of STING agonism combined ...
Yueyao Wu   +11 more
wiley   +1 more source

ROS‐Responsive Eye Drop for Controlled Release of 20‐Deoxyingenol Improves Diabetic Corneal Healing by Activating Macrophage Autophagy and Metabolic Reprogramming

open access: yesAdvanced Science, EarlyView.
Schematic illustration of ROS‐responsive TSPBA‐PVA microspheres loaded with 20‐deoxyingenol (TP/20‐DOI) for diabetic corneal wound healing: (a) fabrication and ROS‐triggered release; (b) autophagy activation and metabolic reprogramming in macrophages; (c) suppression of macrophage‐derived CXCL3/CXCL5, attenuation of neutrophil infiltration, and ...
Jiaxin Wu   +20 more
wiley   +1 more source

Effect of Phone Text Message Reminders on Compliance with Rabies Post-Exposure Prophylaxis following Dog Bites in Rural Kenya. [PDF]

open access: yesVaccines (Basel), 2023
Chuchu VM   +11 more
europepmc   +1 more source

Dog bites: what can social media tell us?

open access: yes, 2015
Dog bite statistics are generally recorded through emergency hospital admissions, however little evidence is available on the dog bites which are less serious; require minor medical treatment through a GP or selftreatment, and limited figures are ...
Oxley, James, Ellis, Clare
core  

Uncoupling Type I Interferon Benefits From Inflammatory Toxicity: Transformer‐Prioritized Precision Agonists for Potent and Safer Cancer Immunotherapy

open access: yesAdvanced Science, EarlyView.
A Transformer‐based AI framework, DLINP, screens millions of compounds to identify Co68, a cobalt‐pincer organometallic complex that biases TLR4‐MD2 signaling toward antitumor interferon activation while suppressing inflammatory toxicity through an early TLR4‐SYK‐STAT1 axis.
Xuefei Guo   +10 more
wiley   +1 more source

Fatal dog bites in New Zealand

open access: yes, 2007
Aims: To examine fatalities from dog bites in New Zealand and review New Zealand's most recent fatalities, and the commonalities they show with dog attacks both in New Zealand and overseas.
David Healey, Healey D.
core  

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