Results 41 to 50 of about 234,807 (237)

ADP‐ribosylation: An emerging regulator of the epigenome

Molecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho, Chenqian Liu, W. Lee Kraus   +2 more
wiley   +1 more source

Geographic variation in access to dog-bite care in Pakistan and risk of dog-bite exposure in Karachi: prospective surveillance using a low-cost mobile phone system.

PLoS Neglected Tropical Diseases, 2013
BackgroundDog-bites and rabies are under-reported in developing countries such as Pakistan and there is a poor understanding of the disease burden. We prospectively collected data utilizing mobile phones for dog-bite and rabies surveillance across nine ...
Syed Mohammad Asad Zaidi, Alain B Labrique, Saira Khowaja, Ismat Lotia-Farrukh, Julia Irani, Naseem Salahuddin, Aamir Javed Khan   +6 more
doaj   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

A cross-sectional study of factors associated with dog ownership in Tanzania [PDF]

, 2008
Background: Mass vaccination of owned domestic dogs is crucial for the control of rabies in sub-Saharan Africa. Knowledge of the proportion of households which own dogs, and of the factors associated with dog ownership, is important for the planning and ...
M Karen Laurenson, Mfinanga, S. G. M., Boden, L.A., Kazwala, R. R., Lisa A Boden, Boden, L. A., Cleaveland, C., Laurenson, M.K., Kazwala, Rudovick R., Kazwala, R.R., Cleaveland, Sarah, Sarah Cleaveland, Boden, Lisa, Knobel, D.L., Laurenson, M. Karen, Knobel, D. L., Knobel, Darryn L., Rudovick R Kazwala, Laurenson, M. K., Cleaveland, S., Darryn L Knobel, Kazwala Rudovick R, Laurenson M Karen, Knobel Darryn L, Boden Lisa A, Cleaveland Sarah   +25 more
core   +1 more source

Diagram of frequencies of dog bites from rabid dogs and those bites causing clinical rabies.

, 2022
(A) An estimated 19% baseline value of dog bites develop into clinical rabies in humans. (B) Traditional healers treat dog bite victims, and due to the 10% estimated baseline value of bites from a rabid dog, the traditional healers have an extremely high
Emily G. Pieracci (3074424), Erin A. Beasley (11979320), Louis H. Nel (8506482), Ryan M. Wallace (8501889), Andre Coetzer (634423)   +4 more
core   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

FEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell, Cassy Ross, Panagiota S. Filippou, Bruno Silvester Lopes, Dominic Gilchrist, Paul Dean, Kamar Ameen‐Ali, Tora K. Smulders‐Srinivasan, Ahmad A. Khundakar   +8 more
wiley   +1 more source

Two Leishmania species circulating in the Kaleybar focus of infantile visceral leishmaniasis, northwest Iran: implications for deltamethrin dog collar intervention

, 2008
Leishmania infantum is the causative agent of infantile visceral leishmaniasis (IVL) in the Mediterranean Basin and, based on isoenzyme typing of a few isolates from patients and domestic dogs, this parasite was considered to predominate in the Kaleybar ...
Ready, P. D. (Paul Donald), Parvizi, P, Mazloumi-Gavgani, A. S., Davies, CR, Ready, PD, Courtenay, Orin, P.D. Ready, P. Parvizi, A.S. Mazloumi-Gavgani, C.R. Davies, Parvizi, P., Courtenay, O, O. Courtenay, Mazloumi-Gavgani, AS, Davies, C. R.   +14 more
core   +1 more source

Posterior Disconnection Syndrome in Early‐Stage Adult‐Onset Cerebral Adrenoleukodystrophy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Adult‐onset cerebral adrenoleukodystrophy is potentially treatable but often difficult to recognize before advanced cerebral involvement. Herein, we describe three men with early‐stage disease who initially presented with subtle visual complaints rather than subcortical dementia. Targeted neuropsychological testing revealed higher‐order visual
Kazuto Katsuse, Takashi Matsukawa, Yumiko Nakamura, Kazuo Kakinuma, Shoko Ota, Ryo Hara, Saki Nakashima, Kaoru Ito, Yutaro Nakamori, Toshiyuki Kakumoto, Masashi Hamada, Shigenori Kanno, Kyoko Suzuki, Tatsushi Toda   +13 more
wiley   +1 more source

Brighter Bites Annual Report 2020 [PDF]

, 2021
Brighter Bites started out the year excited about our program's expansion and growth to our seventh market, Salinas, California; then the pandemic changed everything.

core   +2 more sources

A retrospective study of dog bite occurrence and anti-rabies vaccination of dogs in a State Veterinary Hospital in Ogoja, Cross River State, Nigeria

Veterinaria Italiana, 2019
Rabies is one of the world’s major zoonoses. Controlling rabies continues to pose a major public health challenge. The issues surrounding dog bites and the vaccination of dogs against rabies are important to consider in implementing programmes to control
Thomas I. Isek, Jarlath Umoh, Asabe A. Dzikwi   +2 more
doaj   +1 more source