Cancer‐associated fibroblasts (CAFs) promote cancer growth, invasion (metastasis), and drug resistance. Here, we identified functional and diverse circulating CAFs (cCAFs) in patients with metastatic prostate cancer (mPCa). cCAFs were found in higher numbers and were functional and diverse in mPCa patients versus healthy individuals, suggesting their ...
Richell Booijink+6 more
wiley +1 more source
A transient inflammatory response contributes to oxaliplatin neurotoxicity in mice
Abstract Objectives Peripheral neuropathy is a relevant dose‐limiting adverse event that can affect up to 90% of oncologic patients with colorectal cancer receiving oxaliplatin treatment. The severity of neurotoxicity often leads to dose reduction or even premature cessation of chemotherapy.
Aina Calls+9 more
wiley +1 more source
Trends in popularity of some morphological traits of purebred dogs in Australia. [PDF]
Background The morphology of dogs can provide information about their predisposition to some disorders. For example, larger breeds are predisposed to hip dysplasia and many neoplastic diseases.
A BergstrÖM+63 more
core +3 more sources
Survey of dog owners’ and veterinarians’ attitudes regarding the selection of flea and tick prevention products in Thailand [PDF]
Background and Aim: Tick and flea infestations in dogs are significant concerns for both dog owners and veterinarians in Thailand. The country’s climate provides an optimal environment for the proliferation of ticks and fleas, thereby increasing the risk
Pornlapas Panchim+5 more
doaj +1 more source
Detecting Pulmonary Coccidioidomycosis (Valley fever) with Deep Convolutional Neural Networks [PDF]
Coccidioidomycosis is the most common systemic mycosis in dogs in the southwestern United States. With warming climates, affected areas and number of cases are expected to increase in the coming years, escalating also the chances of transmission to humans. As a result, developing methods for automating the detection of the disease is important, as this
arxiv
A comparative study of circulating tumor cell isolation and enumeration technologies in lung cancer
Lung cancer cells were spiked into donor blood to evaluate the recovery rates of the following circulating tumor cell (CTC) enrichment technologies: CellMag™, EasySep™, RosetteSep™, Parsortix® PR1, and Parsortix® Prototype systems. Each method's advantages and disadvantages are described.
Volga M Saini+11 more
wiley +1 more source
Recognizing early MRI signs (or their absence) is crucial in diagnosing metachromatic leukodystrophy
Abstract Objectives Metachromatic leukodystrophy (MLD) has characteristic white matter (WM) changes on brain MRI, which often trigger biochemical and genetic confirmation of the diagnosis. In early or pre‐symptomatic disease stages, these typical MRI changes might be absent, hampering early diagnosis.
Daphne H. Schoenmakers+7 more
wiley +1 more source
Certified service dogs - A cost-effectiveness analysis appraisal.
IntroductionIndividuals with functional impairments or chronic diseases are often in need of assistance in their daily lives. For these individuals it is essential to find novel, cost-effective solutions to meet their needs.
Martina Lundqvist+2 more
doaj +1 more source
Atlas of Ear Diseases of the Dog and Cat
DESCRIPTION Bringing together a wealth of images of normal and diseased dog and cat ears, this is an indispensible diagnostic tool for the small animal veterinary practitioner seeing ear cases on a regular basis.
S. Paterson, K. Tobias
semanticscholar +1 more source
Development of Dog Immune System: From in Uterus to Elderly
Immune system recognize and fight back foreign microorganisms and inner modifications that lead to deficient cell and tissue functions. During a dog’s life, the immune system needs to adapt to different physiological conditions, assuring surveillance and
M. Pereira+5 more
semanticscholar +1 more source