Results 101 to 110 of about 9,464,894 (393)

KRAS and GNAS mutations in cell‐free DNA and in circulating epithelial cells in patients with intraductal papillary mucinous neoplasms—an observational pilot study

open access: yesMolecular Oncology, EarlyView.
This study demonstrates that KRAS and GNAS mutations are more prevalent in patients with resected intraductal papillary mucinous neoplasms (IPMN) compared to those under clinical surveillance. GNAS mutations significantly differ between the two patient cohorts, indicating that their absence may serve as a potential biomarker to support conservative ...
Christine Nitschke   +12 more
wiley   +1 more source

Dog size and patterns of disease history across the canine age spectrum: Results from the Dog Aging Project.

open access: yesPLoS ONE
Age in dogs is associated with the risk of many diseases, and canine size is a major factor in that risk. However, the size patterns are complex. While small size dogs tend to live longer, some diseases are more prevalent among small dogs.
Yunbi Nam   +6 more
doaj   +1 more source

Unusual case of pleural effusion caused by amlodipine in a dog with systemic hypertension

open access: yesVeterinary Medicine and Science, 2022
Objective The aim of this report is to document the case of a dog that developed pleural effusion as a potential side‐effect to the administration of a high‐dose of amlodipine.
Hee‐Won Jang   +8 more
doaj   +1 more source

Time-activity budget of urban-adapted free-ranging dogs [PDF]

open access: yesActa Ethologica 25, 2022, 2019
The domestic dog is known to have evolved from gray wolves, about 15,000 years ago. They majorly exist as free-ranging populations across the world. They are typically scavengers and well adapted to living among humans. Most canids living in and around urban habitats tend to avoid humans and show crepuscular activity peaks.
arxiv   +1 more source

Targeting rapid TKI‐induced AXL upregulation overcomes adaptive ERK reactivation and exerts antileukemic effects in FLT3/ITD acute myeloid leukemia

open access: yesMolecular Oncology, EarlyView.
Adaptive ERK reactivation hinders FLT3 tyrosine kinase inhibitor (TKI) treatment in FLT3/ITD acute myeloid leukemia. Here, we report that FLT3 TKI treatment rapidly induces AXL expression and upregulation that is temporally associated with the adaptive ERK reactivation.
Tessa S. Seale   +9 more
wiley   +1 more source

Periodontal Disease in Dogs [PDF]

open access: yes, 2012
Periodontal disease is the most common oral disease in dogs with up of 80% of animals affected (Riggio et al., 2011). This disease is progressive and involves two stages: gingivitis (reversible) and periodontitis (irreversible, but often controllable). It is caused by plaque buildup on teeth. The plaque is a smooth membrane, adhesive, contaminated with
Fbio Alessandro   +3 more
openaire   +2 more sources

Introduction of Asian canine parvovirus in Europe through dog importation

open access: yesTransboundary and Emerging Diseases, 2017
Summary Canine parvovirus (CPV) is an important infectious agent of domestic and wild carnivores, responsible for severe and often fatal haemorrhagic gastroenteritis and leukopenia.
F. Mira   +8 more
semanticscholar   +1 more source

Combined spatially resolved metabolomics and spatial transcriptomics reveal the mechanism of RACK1‐mediated fatty acid synthesis

open access: yesMolecular Oncology, EarlyView.
The authors analyzed the spatial distributions of gene and metabolite profiles in cervical cancer through spatial transcriptomic and spatially resolved metabolomic techniques. Pivotal genes and metabolites within these cases were then identified and validated.
Lixiu Xu   +3 more
wiley   +1 more source

Largest dog genetic study informs human diseases [PDF]

open access: yes, 2016
The news item from the Cornell Chronicle is about: Cornell researchers have completed the largest genetic study of dogs to date, comprising the genetic analysis of 4,200 dogs.
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