Results 111 to 120 of about 9,464,894 (393)

Integrative systems‐level analysis reveals a contextual crosstalk between hypoxia and global metabolism in human breast tumors

Molecular Oncology, EarlyView.
Breast tumor samples scored for metabolic deregulation (M1 to M3) were given a hypoxia score (HS). The highest HS occurred in patients with strongest metabolic deregulation (M3), supporting tumor aggressiveness. HS correlated with the highest number of metabolic pathways in M1. This suggests hypoxia to be an early event in metabolic deregulation.
Raefa Abou Khouzam, Salem Chouaib, Mohammad Askandar Iqbal   +2 more
wiley   +1 more source

Trends in Allergic Sensitization and Diseases in the Korean General Population Over a 9-Year Period [PDF]

Clinical and Experimental Otorhinolaryngology
Objectives. The prevalence of allergic sensitization and diseases varies over time due to changes in climate, environment, and lifestyle. This study analyzed changes in sensitization to house dust mites (HDM) and dogs, as well as the prevalence of ...
Dong Hee Lee, Ji-Hyeon Shin
doaj   +1 more source

System Configuration and Navigation of a Guide Dog Robot: Toward Animal Guide Dog-Level Guiding Work [PDF]

arXiv, 2022
A robot guide dog has compelling advantages over animal guide dogs for its cost-effectiveness, potential for mass production, and low maintenance burden. However, despite the long history of guide dog robot research, previous studies were conducted with little or no consideration of how the guide dog handler and the guide dog work as a team for ...
arxiv  

Barriers to dog rabies vaccination during an urban rabies outbreak: Qualitative findings from Arequipa, Peru

PLoS Neglected Tropical Diseases, 2017
Background Canine rabies was reintroduced to the city of Arequipa, Peru in March 2015. The Ministry of Health has conducted a series of mass dog vaccination campaigns to contain the outbreak, but canine rabies virus transmission continues in Arequipa’s ...
R. Castillo-Neyra, Joanna Brown, Katty Borrini, C. Arevalo, M. Levy, A. Buttenheim, Gabrielle C. Hunter, Victor Becerra, Jere r. Behrman, V. Paz-Soldán   +9 more
semanticscholar   +1 more source

Crosstalk between gut microbiota and tumor: tumors could cause gut dysbiosis and metabolic imbalance

Molecular Oncology, EarlyView.
In this research, we analyzed the relationship between gut microbiota and tumor. We discovered that both subcutaneous and metastatic tumors would alter the composition and metabolic function of gut microbiota. Meanwhile, fecal microbiota transplantation also indicated the anti‐tumor role of the gut microbiota, revealing the crosstalk between tumor and ...
Siyuan Zhang, Haimei Wen, Ying Chen, Jingya Ning, Di Hu, Yujiao Dong, Chenyu Yao, Bo Yuan, Shuanying Yang   +8 more
wiley   +1 more source

The accumulation of myeloid‐derived suppressor cells participates in abdominal infection‐induced tumor progression through the PD‐L1/PD‐1 axis

Molecular Oncology, EarlyView.
This study explores how sepsis affects GC progression by creating an immunosuppressive environment. Our findings reveal that sepsis promotes immune dysregulation, enhancing tumor growth and metastasis. Targeting the PD‐1/PD‐L1 pathway with monoclonal antibodies shows potential for restoring immune function and improving outcomes in cancer patients ...
Yiding Wang, Ting Guo, Xiaofang Xing, Xijuan Liu, Xuejun Gan, Yingai Li, Yan Liu, Fei Shan, Zhouqiao Wu, Jiafu Ji, Ziyu Li   +10 more
wiley   +1 more source

Multiple morbidities in companion dogs: a novel model for investigating age-related disease [PDF]

, 2016
The proportion of men and women surviving over 65 years has been steadily increasing over the last century. In their later years, many of these individuals are afflicted with multiple chronic conditions, placing increasing pressure on healthcare systems.
Delignette-Muller ML, DuGoff EH, R Core Team, Treuting PM, Venables WN, Yancik R   +5 more
core   +2 more sources

Prostate Diseases in the Dog [PDF]

Acta Veterinaria Brno, 1998
A retrospective study is presented of prostatic diseases diagnosed in 32 dogs over a period of 26 years in a private veterinary practice.Of the 32 diseased dogs, 19 patiens were aged 6-10 years, 11 dogs were 11-15 years of age, and 2 animals were younger than 5 years.An unusual case of prostate carcinoma in a 2-year-old Dobermann is documented.Based on
K. Čuljak, M. Hadiosmanovič, Rinck J., B. Njari, M. Rinck, M. Vučemilo, R. Rinck, R. Sabočanec   +7 more
openaire   +2 more sources

Cost-effectiveness of dog rabies vaccination programs in East Africa

PLoS Neglected Tropical Diseases, 2018
Background Dog rabies annually causes 24,000–70,000 deaths globally. We built a spreadsheet tool, RabiesEcon, to aid public health officials to estimate the cost-effectiveness of dog rabies vaccination programs in East Africa.
R. Borse, Charisma Y. Atkins, M. Gambhir, E. Undurraga, J. Blanton, E. Kahn, J. Dyer, C. Rupprecht, M. Meltzer   +8 more
semanticscholar   +1 more source

Robust acute myeloid leukemia engraftment in humanized scaffolds using injectable biomaterials and intravenous xenotransplantation

Molecular Oncology, EarlyView.
Patient‐derived xenografts (PDXs) can be improved by implantation of a humanized niche. We tested different biomaterials and approaches, and demonstrate that the combination of an injectable biomaterial for scaffold creation plus an intravenous route for acute myeloid leukemia (AML) xenotransplantation provide the most convenient and robust approach to
Daniel Busa, Zdenka Herudkova, Jan Hyl, Jakub Vlazny, Filip Sokol, Kvetoslava Matulova, Adam Folta, Jakub Hynst, Lucy Vojtova, Leos Kren, Martin Repko, Zdenek Racil, Jiri Mayer, Martin Culen   +13 more
wiley   +1 more source