Results 121 to 130 of about 9,518,717 (373)

Cat and dog ownership during/after the first year of life and risk for sensitization and reported allergy symptoms at age 13

Immunity, Inflammation and Disease, 2019
Background Avoidance of pets as a strategy for preventing atopic diseases has been questioned. This study aimed to identify the risk of sensitization and allergic symptoms at age 13 in relation to dog‐ and cat‐keeping during and after the first year of ...
Chaifa Al‐Tamprouri, Barman Malin, Hesselmar Bill, Bråbäck Lennart, Sandin Anna   +4 more
doaj   +1 more source

Scoping decades of dog evidence: a scoping review of dog bite-related sequelae

Canadian journal of public health, 2018
ObjectivesThere has been considerable literature published focusing on various sequelae to dog bites over the last three decades. Much of the literature has focused on rabies, particularly canine rabies variant, which accounts for the majority of rabies ...
J. Dhillon, J. Hoopes, T. Epp
semanticscholar   +1 more source

Evaluation and modification of tumor cell isolation techniques from malignant effusions for rapid drug sensitivity testing

Molecular Oncology, EarlyView.
Non‐small cell lung cancer targeted treatment is limited to a few known genetic alterations, with few alternatives in advanced treatment lines. To direct treatment decisions by drug sensitivity testing (DST), this study compared several methods for tumor cell isolation from malignant effusions, pointing to repeated CD45+ cell depletion for effective ...
Navit Mooshayef, Hana Barhom, Sumit Chatterji, Netta Hecht, Oran Warhaftig, Iris Kamer, Oranit Zadok, Jair Bar, Limor Broday, Amir Onn, Michael Peled   +10 more
wiley   +1 more source

The DoGA consortium expression atlas of promoters and genes in 100 canine tissues

Nature Communications
The dog, Canis lupus familiaris, is an important model for studying human diseases. Unlike many model organisms, the dog genome has a comparatively poor functional annotation, which hampers gene discovery for development, morphology, disease, and ...
Matthias Hörtenhuber, Marjo K. Hytönen, Abdul Kadir Mukarram, Meharji Arumilli, César L. Araujo, Ileana Quintero, Pernilla Syrjä, Niina Airas, Maria Kaukonen, Kaisa Kyöstilä, Julia Niskanen, Tarja S. Jokinen, Faezeh Mottaghitalab, Işıl Takan, Noora Salokorpi, Amitha Raman, Irene Stevens, Antti Iivanainen, Masahito Yoshihara, Oleg Gusev, Danika Bannasch, Antti Sukura, Jeffrey J. Schoenebeck, DoGA Consortium, Sini Ezer, Shintaro Katayama, Carsten O. Daub, Juha Kere, Hannes Lohi   +28 more
doaj   +1 more source

Biology and Diseases of Dogs

, 2015
Historically, the dog played an important role as a laboratory animal in biomedical research. Although numbers are declining, the use of dogs continues to be common in pharmacokinetics and cardiovascular studies. The normal biology of the dog as both a laboratory and a companion animal has been well studied and reference values are presented here as a ...
Nemzek, Jean A., Lester, Patrick A., Wolfe, A. Marissa, Dysko, Robert C., Myers, Daniel D.   +4 more
openaire   +1 more source

Towards elimination of dog-mediated human rabies: experiences from implementing a large-scale demonstration project in Southern Tanzania [PDF]

, 2017
No abstract ...
Abela-Ridder, Bernadette, Changalucha, Joel, Cleaveland, Sarah, Hampson, Katie, Jaswant, Gurdeep, Kazwala, Rudovick, Lembo, Tiziana, Lushasi, Kennedy, Makungu, Selemani, Mancy, Rebecca, Maziku, Matthew, Mbunda, Eberhard M., Mchau, Geofrey, Meslin, François-Xavier, Mpolya, Emmanuel Abraham, Mtema, Zacharia, Nanai, Alphoncina, Ngeleja, Chanasa, Rysava, Kristyna, Sambo, Maganga, Sikana, Lwitiko, Townsend, Sunny   +21 more
core   +1 more source

Cytomegalovirus infection is common in prostate cancer and antiviral therapies inhibit progression in disease models

Molecular Oncology, EarlyView.
Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon, Moa Stenudd, Margherita Zamboni, Kanar Alkass, Carl‐Johan Eriksson, Lars Pedersen, Alrik Schörling, Anna Thoss, Anders Bergh, Pernilla Wikström, Hans‐Olov Adami, Henrik Toft Sørensen, Henrik Druid, Jonas Frisén   +13 more
wiley   +1 more source

Targeting carbonic anhydrase IX/XII prevents the anti‐ferroptotic effect of stromal lactic acid in prostate carcinoma

Molecular Oncology, EarlyView.
In prostate carcinoma, lactic acid, secreted by highly glycolytic cancer‐associated fibroblasts, is imported into tumor cells through the MCT1 transporter and prevents RSL3 and erastin‐induced ferroptosis (A). Targeting of carbonic anhydrase IX/XII, the main extracellular pH regulators, in tumor and stromal cells reduces microenvironmental acidosis and
Elisa Pardella, Giuseppina Comito, Luigi Ippolito, Erica Pranzini, Marta Iozzo, Giulia Gangarossa, Francesca Virgilio, Silvia Bua, Alessio Nocentini, Giada Sandrini, Nicla Lorito, Marina Bacci, Gabriella Nesi, Pietro Spatafora, Sergio Serni, Claudiu T. Supuran, Andrea Morandi, Paola Chiarugi, Elisa Giannoni   +18 more
wiley   +1 more source

Neoplasmas da tireoide em cães: 26 casos

Pesquisa Veterinária Brasileira
RESUMO: Foram revisados os protocolos de biópsias e necropsias do Laboratório de Patologia Veterinária da Universidade Federal de Santa Maria (LPV/UFSM) entre 2004 e 2014, e todos os casos de tumores que acometeram a glândula tireoide foram selecionados.
Camila Tochetto, Taiara M. da Silva, Rafael A. Fighera, Luiz Francisco Irigoyen, Glaucia D. Kommers   +4 more
doaj   +1 more source

Spontaneous Renal Disease in Dogs [PDF]

Toxicologic Pathology, 1986
Renal disease is common in dogs. The incidence of significant renal disease increases with age. Many disease processes are subtle and subacute, and so many are not detected until they result in chronic renal failure. The causes of many renal diseases are not known but one must suspect immune-mediated damage in some.
openaire   +3 more sources