Results 121 to 130 of about 9,464,894 (393)
Targeted metabolomics reveals novel diagnostic biomarkers for colorectal cancer
Molecular Oncology, EarlyView.This study employed targeted metabolomic profiling to identify 302 distinct metabolites present in platelet‐rich plasma (PRP), revealing aberrant metabolic profiles amongst individuals diagnosed with colorectal cancer (CRC). Compared to carcinoembryonic antigen (CEA) and cancer antigen 19‐9 (CA199), our metabolite panel showed improved sensitivity ...
Zuojian Hu +7 more
wiley +1 more source
Barriers of attendance to dog rabies static point vaccination clinics in Blantyre, Malawi
PLoS Neglected Tropical Diseases, 2018 Rabies is a devastating yet preventable disease that causes around 59,000 human deaths annually. Almost all human rabies cases are caused by bites from rabies-infected dogs. A large proportion of these cases occur in Sub Saharan Africa (SSA).
S. Mazeri +6 more
semanticscholar +1 more source
KMT2A degradation is observed in decitabine‐responsive acute lymphoblastic leukemia cells
Molecular Oncology, EarlyView.We demonstrate that decitabine (DEC) not only degrades the DNA methyltransferase DNMT1 but also the leukemic driver lysine methyltransferase KMT2A likely due to structural similarity of the DNA‐binding CXXC domains. DEC influences KMT2A downstream processes and synergizes with menin inhibitor revumenib (REV) to decrease leukemic cell proliferation, and
Luisa Brock +10 more
wiley +1 more source
A short report on epidemiological investigation of dog bite cases in association with temperature rise as a part of climate change [PDF]
, 2019 Background: Rabies is a neglected disease that claims more than 5000 human’s deaths in Pakistan that account for 10% global load of rabies related deaths annually. Dogs are major carriers for this zoonotic ailment in the country. Global climatic changes,
Ahmed, Touseef +3 more
core +1 more source
Development of learning objectives for neurology in a veterinary curriculum: Part II: Postgraduates [PDF]
, 2015 Background: Specialization in veterinary medicine in Europe is organized through the Colleges of the European Board of Veterinary Specialization. To inform updating of the curriculum for residents of the European College of Veterinary Neurology (ECVN ...
Anderson, T J +13 more
core +5 more sources
Acta Veterinaria Scandinavica, 2020 Canine vector-borne diseases are caused by pathogens transmitted by arthropods including ticks, mosquitoes and sand flies. Many canine vector-borne diseases are of zoonotic importance.
Cristina Daniela Cazan +6 more
doaj +1 more source
The Structural Stability of Wild-type Horse Prion Protein - Molecular Dynamics Studies [PDF]
J Biomol Struct Dyn 29 (2) 369-377 (2013), 2011 Prion diseases {\it (e.g. Creutzfeldt-Jakob disease (CJD), variant CJD (vCJD), Gerstmann-Str$\ddot{\text{a}}$ussler-Scheinker syndrome (GSS), Fatal Familial Insomnia (FFI) and Kuru in humans, scrapie in sheep, bovine spongiform encephalopathy (BSE or `mad-cow' disease) and chronic wasting disease (CWD) in cattles)} are invariably fatal and highly ...
arxiv
Molecular Oncology, EarlyView.Transient receptor potential melastatin‐4 (TRPM4) is overexpressed in prostate cancer (PCa). Knockout of TRPM4 resulted in reduced PCa tumor spheroid size and decreased PCa tumor spheroid outgrowth. In addition, lack of TRPM4 increased cell death in PCa tumor spheroids.
Florian Bochen +6 more
wiley +1 more source
Renewed global partnerships and redesigned roadmaps for rabies prevention and control [PDF]
, 2011 Canine rabies, responsible for most human rabies deaths, is a serious global public health concern. This zoonosis is entirely preventable, but by focusing solely upon rabies prevention in humans, this "incurable wound" persists at high costs.
Attlan, Michael +18 more
core +5 more sources