Results 131 to 140 of about 9,518,717 (373)

Bioengineering facets of the tumor microenvironment in 3D tumor models: insights into cellular, biophysical and biochemical interactions

open access: yesFEBS Open Bio, EarlyView.
The tumor microenvironment is a dynamic, multifaceted complex system of interdependent cellular, biochemical, and biophysical components. Three‐dimensional in vitro models of the tumor microenvironment enable a better understanding of these interactions and their impact on cancer progression and therapeutic resistance.
Salma T. Rafik   +3 more
wiley   +1 more source

Tuberculose canina e sua importância em saúde pública

open access: yesRevista de Saúde Pública
Relata-se um caso de uma família com diagnóstico de tuberculose, cujo cão também apresentava a enfermidade. Discute-se a importância do rastreamento epidemiológico animal em casos de tuberculose humana.
Jane Megid   +5 more
doaj  

Painted Ferocity: The Social Behaviors of African Wild Dogs, Threats to Survival, and Resulting Conservation Initiatives [PDF]

open access: yes, 2018
African Wild Dogs (Lycaon pictus) are an endangered species of canid from Sub-Saharan Africa. They are very social communal hunters, and are capable of chasing down prey for long stretches of time. Wild dogs benefit a savannah ecosystem by regulating the
Valdes, Alexis
core   +1 more source

Comparative single‐cell transcriptomic profiling of patient‐derived renal carcinoma cells in cellular and animal models of kidney cancer

open access: yesFEBS Open Bio, EarlyView.
We generated and characterized clear cell renal cell carcinoma models using the patient‐derived RCC243 cell line—including cell culture, orthotopic, and metastatic tumors—via single‐cell RNA‐sequencing for comparisons between models and patient tumor datasets.
Richard Huang   +9 more
wiley   +1 more source

Pattern and outcome of dog bite injuries among children in Ado-Ekiti, Southwest Nigeria

open access: yesThe Pan African Medical Journal, 2017
Introduction: dog bites in humans are a major public health problem. Globally, millions of people are bitten by dogs but most of the fatal cases occur in children. There is paucity of data on dog bite related diseases among Nigerian children. Objectives:
Ezra Olatunde Ogundare   +7 more
doaj   +1 more source

METTL3 knockout accelerates hepatocarcinogenesis via inhibiting endoplasmic reticulum stress response

open access: yesFEBS Open Bio, EarlyView.
Liver‐specific knockout of N6‐methyladenosine (m6A) methyltransferase METTL3 significantly accelerated hepatic tumor initiation under various oncogenic challenges, contrary to the previously reported oncogenic role of METTL3 in liver cancer cell lines or xenograft models. Mechanistically, METTL3 deficiency reduced m6A deposition on Manf transcripts and
Bo Cui   +15 more
wiley   +1 more source

Transmission dynamics of re-emerging rabies in domestic dogs of rural China.

open access: yesPLoS Pathogens, 2018
Despite ongoing efforts to control transmission, rabies prevention remains a challenge in many developing countries, especially in rural areas of China where re-emerging rabies is under-reported due to a lack of sustained animal surveillance.
Huaiyu Tian   +15 more
doaj   +1 more source

Advanced glycation end products promote the release of endothelial cell‐derived mitocytosis

open access: yesFEBS Open Bio, EarlyView.
Under diabetic conditions, AGEs induce mitochondrial damage in HUVECs, activating migrasome‐mediated mitocytosis. Migrasomes encapsulate damaged mitochondria and are released into the extracellular space, facilitating intercellular mitochondrial transfer.
Rong Liu   +6 more
wiley   +1 more source

Knowledge and attitudes about tetanus and rabies: a population-based survey from Karachi, Pakistan [PDF]

open access: yes, 2012
OBJECTIVE: To evaluate public knowledge regarding predisposing factors, fatality and prevention of Tetanus and Rabies and attitudes toward vaccination and post-exposure prophylaxis. METHODS: A population-based, cross-sectional survey was conducted in all
Azam, Iqbal   +8 more
core   +1 more source

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