Computational Studies of the Structural Stability of Rabbit Prion Protein Compared to Human and Mouse Prion Proteins [PDF]
Prion diseases are invariably fatal and highly infectious neurodegenerative diseases affecting humans and animals. The neurodegenerative diseases such as Creutzfeldt-Jakob disease, variant Creutzfeldt-Jakob diseases, Gerstmann-Str$\ddot{a}$ussler-Scheinker syndrome, Fatal Familial Insomnia, Kuru in humans, scrapie in sheep, bovine spongiform ...
Zhang, Jiapu
arxiv +5 more sources
Molecular Dynamics Studies of Dog Prion Protein Wild-type and Its D159N Mutant [PDF]
Prion diseases (e.g. "mad cow" disease in cattle, chronic wasting disease in deer and elk, CJD in humans) have been a major public health concern affecting humans and almost all animals. However, dogs are strongly resistant to prion diseases. Recently, it was reported that the single (surface) residue D159 is sufficient to confer protection against ...
Zhang, Jiapu
arxiv +5 more sources
Awareness, Knowledge, and Perceptions Regarding Rabies Prevention Among Rural Communities in Masaka District, Central Uganda: A Qualitative Study [PDF]
Rabies is a zoonotic disease that is mainly transmitted to humans through dog bites. It remains a major public health threat in many Asian and African countries, including Uganda.
Clovice Kankya+10 more
doaj +4 more sources
The DoGA consortium expression atlas of promoters and genes in 100 canine tissues [PDF]
The dog, Canis lupus familiaris, is an important model for studying human diseases. Unlike many model organisms, the dog genome has a comparatively poor functional annotation, which hampers gene discovery for development, morphology, disease, and ...
Matthias Hörtenhuber+28 more
doaj +5 more sources
Understanding hereditary diseases using the dog and human as companion model systems [PDF]
Animal models are requisite for genetic dissection of, and improved treatment regimens for, human hereditary diseases. While several animals have been used in academic and industrial research, the primary model for dissection of hereditary diseases has ...
K. Tsai, L. A. Clark, K. Murphy
semanticscholar +3 more sources
Analyzing large-scale DNA Sequences on Multi-core Architectures [PDF]
Rapid analysis of DNA sequences is important in preventing the evolution of different viruses and bacteria during an early phase, early diagnosis of genetic predispositions to certain diseases (cancer, cardiovascular diseases), and in DNA forensics. However, real-world DNA sequences may comprise several Gigabytes and the process of DNA analysis demands
Memeti, Suejb, Pllana, Sabri
arxiv +3 more sources
Designing programs for eliminating canine rabies from islands: Bali, Indonesia as a case study [PDF]
<p>Background: Canine rabies is one of the most important and feared zoonotic diseases in the world. In some regions rabies elimination is being successfully coordinated, whereas in others rabies is endemic and continues to spread to uninfected ...
AAG Putra+51 more
core +25 more sources
Community perceptions of free-roaming dogs and management practices in villages at the periphery of a protected area in Bhutan [PDF]
In Bhutan, free-roamingdogs pose health hazards to human, livestock, andwildlife. Understanding the perceptions and practices of local communitiesregarding free-roaming dogs is important to mitigate negative impacts. A community-based study was conducted
De Garine-Wichatitsky, Michel+4 more
core +1 more source
The Design Challenges for Dog Ownership and Dog Walking in Dense Urban Areas: The Case of Japan
There has been growing interest in the role of pet ownership, particularly dog ownership, in managing noncommunicable diseases. The built environment can act as a facilitator or barrier to owning a dog or dog walking.
Mohammad Javad Koohsari+9 more
doaj +1 more source
Possible Human-to-Dog Transmission of SARS-CoV-2, Italy, 2020
We detected severe acute respiratory syndrome coronavirus 2 in an otherwise healthy poodle living with 4 family members who had coronavirus disease. We observed antibodies in serum samples taken from the dog, indicating seroconversion. Full-length genome
N. Decaro+17 more
semanticscholar +1 more source