Results 201 to 210 of about 329,272 (305)

Microfluidic Modeling of Macrophage‐Induced Cardiac Inflammation Using NF‐κB Reporter Cardiomyocytes

open access: yesAdvanced Healthcare Materials, EarlyView.
A cardiac inflammation model was developed to enable real‐time analysis of macrophage‐cardiomyocyte interactions using NF‐κB‐reporter cardiomyocytes and a microfluidic co‐culture system. A MATLAB‐based model was implemented to optimize cell density and medium resupply based on TNFα diffusion kinetics. Activation thresholds and stress responses in NF‐κB‐
Chao Liu   +6 more
wiley   +1 more source

An Edible H2O2 Biosensor for Gastrointestinal Metabolites and Peroxidase Enzyme Quantification

open access: yesAdvanced Healthcare Materials, EarlyView.
We present an edible biosensor for gastric fluid analysis that integrates a caffeic acid–horseradish peroxidase redox system into an edible electrolyte‐gated transistor. The device enables rapid, low‐volume detection of H2O2 and, with minimal modification, metabolites and enzyme activity in simulated gastrointestinal conditions.
Valerio Francesco Annese   +10 more
wiley   +1 more source

Ovarian T-cell lymphoma in a dog with chronic protein-losing enteropathy. [PDF]

open access: yesActa Vet Scand
Mortensen JK   +2 more
europepmc   +1 more source

Fluid Forces Control Structural Remodeling of Blind‐Ended Lymphatic Microvessels

open access: yesAdvanced Healthcare Materials, EarlyView.
Using innovative microfluidic biofabrication with fluid mechanical insights, we recapitulated the blind‐ended microanatomy and physiological drainage properties of capillary lymphatics. Our results reveal the interrelationship between intra‐ and extraluminal regions of lymphatic vessels due to flow‐induced sprouting and morphological changes that ...
Jacob C. Holter   +5 more
wiley   +1 more source

Decellularized Extracellular Matrix (dECM) in Tendon Regeneration: A Comprehensive Review

open access: yesAdvanced Healthcare Materials, EarlyView.
Decellularized Extracellular Matrix (dECM) offers a promising solution by replicating the native tendon microenvironment and promoting regeneration. This review highlights advances in the decellularization methods, as well as their integration with emerging technologies and translational progress in tendon tissue engineering.
Kumaresan Sakthiabirami   +4 more
wiley   +1 more source

Simvastatin Restores Uteroplacental Hemodynamics and Trophoblast Function in Obstetric Antiphospholipid Syndrome in a Placenta‐on‐a‐Chip Model

open access: yesAdvanced Healthcare Materials, EarlyView.
Simvastatin mitigates placental hypoperfusion in OAPS by ameliorating abnormal uteromaternal hemodynamics and enhancing trophoblast invasion via optimized endothelial cell interactions under pathological shear stress, as evidenced by results from a placenta‐on‐a‐chip platform.
Hongli Liu   +10 more
wiley   +1 more source

OLD DOG - Validating the dog as an animal model for human aging studies. [PDF]

open access: yesJ Frailty Aging
Zemko P   +5 more
europepmc   +1 more source

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