Results 51 to 60 of about 2,403,217 (301)

Discerning protein pools by selective staining with self‐labeling tags

FEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

Domestic dog ownership in Iran is a risk factor for human infection with Leishmania infantum. [PDF]

, 2002
One explanation proposed for the widespread failure to control zoonotic visceral leishmaniasis by culling infected domestic dogs is that wild canids or humans play significant roles in transmission.
Hassan Mohite, Mohite, Hassan, Mohebali, Mehdi, A Samad Mazloumi Gavgani, Gavgani, A Samad Mazloumi, Gholan H Edrissian, Clive R Davies, Mehdi Mohebali, Edrissian, Gholan H, Davies, Clive R   +9 more
core   +1 more source

Certified service dogs - A cost-effectiveness analysis appraisal.

PLoS ONE, 2019
IntroductionIndividuals with functional impairments or chronic diseases are often in need of assistance in their daily lives. For these individuals it is essential to find novel, cost-effective solutions to meet their needs.
Martina Lundqvist, Jenny Alwin, Lars-Åke Levin   +2 more
doaj   +1 more source

The effectiveness of treatment for dirofilariasis in dogs

Науковий вісник Львівського національного університету ветеринарної медицини та біотехнологій імені С.З. Ґжицького: Серія Ветеринарні науки, 2022
Livestock industry – dog breeding is of great importance in human activities. Infectious and invasive diseases are a deterrent to the breeding and improvement of dog breeds. Not only do they cause significant economic damage to dog breeding, but they can
D. Kryvoruchenko
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Transmission dynamics and prospects for the elimination of canine rabies [PDF]

, 2009
Rabies has been eliminated from domestic dog populations in Western Europe and North America, but continues to kill many thousands of people throughout Africa and Asia every year.
Packer, C., Katie Hampson, Daniel T Haydon, Dobson, A., Magai Kaare, Dobson, Andy, Hampson, K., Packer, Craig, Dobson A., Hampson, Katie, Craig Packer, Packer C., Dushoff, Jonathan, Kaare, M., Dushoff J., Dushoff Jonathan, Haydon, Daniel T., Dobson Andy, Packer Craig, Dushoff, J., Rupprecht, C.E., Cleaveland, S., Jonathan Dushoff, Haydon D.T., Haydon Daniel T, Kaare, Magai, Haydon, D.T, Haydon, D.T., Kaare M., Hampson Katie, Cleaveland S., Cleaveland, Sarah, Sarah Cleaveland, Hampson K., Kaare Magai, Andy Dobson, Cleaveland Sarah   +36 more
core   +1 more source

Sensitive, non-invasive detection of chronic wasting disease in wild and captive white-tailed deer using fecal volatile profiling

mSphere
Chronic wasting disease (CWD) is a universally fatal, transmissible prion disease affecting cervids. Primarily found among deer populations in North America, the disease has spread across the continent and made forays into Europe and Asia as well ...
Amalia Z. Berna, Tzvi Y. Pollock, Yang Liu, Michelle Gibison, Amritha Mallikarjun, Joey Logan, Cynthia M. Otto, Audrey R. Odom John   +7 more
doaj   +1 more source

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source

D159 and S167 are protective residues in the prion protein from dog and horse, two prion-resistant animals

Neurobiology of Disease, 2018
Prion diseases are fatal neurodegenerative diseases caused by misfolding of the prion protein (PrP). These conditions affect humans and animals, including endemic forms in sheep and deer.
Jonatan Sanchez-Garcia, Pedro Fernandez-Funez   +1 more
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source