Results 31 to 40 of about 36,499 (267)
Autoantigen mRNA‐LNP Vaccination Drives Therapeutic Efficacy in Preclinical Models for Autoimmunity
Advanced Science, EarlyView.Systemic and intramuscular delivery of autoantigen mRNA via lipid nanoparticles reprograms antigen‐presenting cells toward a mature, homeostatic state, driving antigen‐specific T cell exhaustion and providing therapeutic efficacy across autoimmune disease models.
Paulien Baeten +30 more
wiley +1 more source
Beauty and Justice in Modern Pentecostal Theological Themes: No Loggerheads [PDF]
Pharos Journal of Theology, 2021 Historically, Pentecostals associate beauty with worldliness. Quest for power, not purity has been at the core of Pentecostal yearnings. Literature review in this article demonstrates that the wheel has made a ‘u-turn’ in this regard..
Dr Kelebogile Thomas Resane (Research Fellow)
doaj
Advanced Science, EarlyView.Aberrant GALNT7‐mediated O‐GalNAcylation stabilizes TAZ to drive gallbladder cancer progression through a feed‐forward transcriptional loop. Structure‐based screening identifies Olaparib as a potent GALNT7 antagonist that disrupts this oncogenic axis, providing an immediate therapeutic strategy for this aggressive malignancy.
Peng Qiu +11 more
wiley +1 more source
The problem of tissue and organ transplantation in the light of the dogma of world religions
Journal of Education, Health and Sport, 2022 Background: Transplantation affects almost everyone, often affecting many almost directly, whether as donor or recipient. The presence of an incurable disease, failure, or irreversible damage to a particular organ leads the patient and his or her ...
Klaudia Magdalena Chatys +6 more
doaj +1 more source
MORMONISM AND PROTESTANTISM: A COMPARATIVE ANALYSIS
Концепт: философия, религия, культура, 2018 The article analyzes in detail the basics and sources of dogma, theological specificity, religious practice, organizational structures of the Church of Jesus Christ of Latter-day Saints and individual Protestant denominations.
E. S. Elbakyan, N. V. Shaburov
doaj +1 more source
A Small‐Molecule DEPTAC Rescues Cognitive Deficits by Targeted Dephosphorylation of Pathological Tau
Advanced Science, EarlyView.TP2 is a fully synthetic small‐molecule dephosphorylation‐targeting chimera that recruits endogenous PP2A‐Bα to Tau, enabling targeted removal of pathological phosphate modifications. In two tauopathy mouse models, systemic TP2 reduces Tau pathology, preserves neuronal and synaptic integrity, improves neuroimmune homeostasis, and rescues cognition ...
Fei Sun +12 more
wiley +1 more source
BJS (British Journal of Surgery), EarlyView., 2020 Clean Cut is a multimodal, adaptive, checklist‐based infection prevention programme designed to improve compliance with six critical perioperative infection prevention practices. After introducing the programme at five hospitals in Ethiopia, compliance with critical infection prevention standards significantly improved and the relative risk of ...
J. A. Forrester +16 more
wiley +1 more source
RNA, 2015 Reflecting on the results of studies of RNA from the last 20 years, one might gain the impression that RNA could be a protein in clever disguise. For decades, RNA had primarily occupied a place in the central dogma of molecular biology as a transient messenger that passively conveys cellular genetic information in a directional flow that starts with ...
Bandyra, Katarzyna, Luisi, Ben
openaire +2 more sources
Advanced Science, EarlyView.A three‐tier livestock multi‐omics framework resolves four typical analytical pitfalls. Moving from statistical association through machine learning preprocessing to triple‐modal causal inference, it converts omics results into genomic selection and gene editing strategies to achieve One Health, underpinned by multi‐omics data, multimodal sequencing ...
Jiying Wen +5 more
wiley +1 more source
Agribusiness, EarlyView.ABSTRACT Innovation is essential for competitiveness in agribusiness facing dynamic environments. This study examines how market orientation, marketing, relational, and social capabilities influence innovation performance. Using data from 751 Spanish firms and a multi‐method approach that integrates Structural Equation Modeling (PLS‐SEM), Necessary ...
Beatriz Corchuelo Martínez‐Azúa +1 more
wiley +1 more source