Results 231 to 240 of about 25,564,378 (356)

Behavioral and genetic analysis of the effects of the psychedelic 2,5-dimethoxy-4-iodoamphetamine (DOI) in C. elegans. [PDF]

PLoS One
White AM, Bauer AD, Faumont S, Lockery SR.   +3 more
europepmc   +1 more source

Structural Characterization and AI‐Enhanced Modeling of a Broadly Neutralizing Camelid Antibody Against SARS‐CoV‐2 Variants

Advanced Therapeutics, EarlyView.
This study characterizes a camelid antibody (B10) with potent neutralizing activity against SARS‐CoV‐2 Wildtype and Omicron variants. Through binding assays, epitope mapping, pseudovirus neutralization, and AI‐driven modeling, the antibody is shown to target conserved RBD regions in a closed Spike conformation.
Katja Hanack, Urszula Orzeł, Anja Schlör, Sourabh Mehta, Anandi Krishnan, Slawomir Filipek, Rushika Patel, Madhvi Joshi, Markus Hoffmann, Stefan Pöhlmann, Chaitanya Joshi, Dorian Liepmann, Ramasamy Paulmurugan, Venkatesan Renugopalakrishnan   +13 more
wiley   +1 more source

Editorial: Climate change challenge: adaptation to climate change. [PDF]

Front Psychol
Carrus G, Massullo C, Tiberio L, Fusaro L, Steinebach C.   +4 more
europepmc   +1 more source

Excessive DNA Double‐Strand Breaks–Associated 3D Genome Reorganization Contributes to Neural Tube Defects with Folate Deficiency

Advanced Science, EarlyView.
Neural tube defects (NTDs) are among the most common congenital malformations. However, the underlying etiology and mechanism remain elusive. Here, the role of DNA double‐strand breaks (DSBs) in 3D genome organization within the NTDs with folate deficiency is reported.
Ting Zhang, Lin Lin, Jianting Li, Caihua Li, Shengjun Liang, Xuemei Bai, Fang Wang, Yihua Bao, Dan Guo, Xiaochen Bo, Hao Li, Hebing Chen, Qiu Xie   +12 more
wiley   +1 more source

Regeneração de plantas híbridas entre Lycopersicon esculentum e L. peruvianum a partir de calos com dois anos de cultura in vitro [PDF]

, 1988
Walter José Siqueira, Monique Ines Segeren Fonseca, Maro R. Sondhal   +2 more
openalex   +1 more source

SURF: A Self‐Supervised Deep Learning Method for Reference‐Free Deconvolution in Spatial Transcriptomics

Advanced Science, EarlyView.
SURF is a robust reference‐free deconvolution tool that integrates high‐dimensional spatial transcriptomics gene expression analysis with self‐supervised deep learning, enabling effective modeling of non‐linear gene interactions and spot relationships.
Shuyu Liang, Zixia Zhou, Peng Huang, Junhu Fu, Jing Jiao, Yunxia Huang, Shichong Zhou, Guanlin Wang, Yuanyuan Wang, Yi Guo   +9 more
wiley   +1 more source

O pré-escolar de dois a seis anos de idade e o seu atendimento [PDF]

, 1981
Yaro Ribeiro Gandra
openalex   +1 more source

Correction: Genome-wide identification, characterization and evolutionary analysis of the pyrroline- 5-carboxylate synthetase (P5CS), succinic semialdehyde dehydrogenase (SSADH), and dehydrin (DHN) genes in Solanum lycopersicum under drought stress. [PDF]

BMC Plant Biol
Maghraby A, Alzalaty M.
europepmc   +1 more source

Human Brain Cell‐Type‐Specific Aging Clocks Based on Single‐Nuclei Transcriptomics

Advanced Science, EarlyView.
Muralidharan and colleagues develop cell‐type‐specific transcriptomic aging clocks using single‐nucleus RNA sequencing of human post mortem prefrontal cortex samples. These clocks accurately predict age and identify distinct aging trajectories in specific brain cell types.
Chandramouli Muralidharan, Enikő Zakar‐Polyák, Anita Adami, Anna A. Abbas, Yogita Sharma, Raquel Garza, Jenny G. Johansson, Diahann A. M. Atacho, Éva Renner, Miklós Palkovits, Csaba Kerepesi, Johan Jakobsson, Karolina Pircs   +12 more
wiley   +1 more source

Combate ao ácaro branco Polyphagotarsonemus tatus (Banks, 1904) em algodão, com defensivos, incluídos dois aplicados por "electrodyn" [PDF]

, 1987
F. A. M. Mariconi, F.I. Geraldi, Cibele Biondo, J.L. Donatoni, A.I. Clari, A.J. Raizer, F.Y. Arashiro   +6 more
openalex   +1 more source