Results 251 to 260 of about 25,482,812 (306)

Photochemical Deracemization of Chromanes and its Application to the Synthesis of Enantiopure Bioactive Compounds

open access: yesAngewandte Chemie, EarlyView.
Various substituted chromane‐2‐carboxamides were successfully deracemized by employing a chiral benzophenone (BP, 10 mol%) as photocatalyst and an achiral thiol as additive (20 mol%). The method was applied to the concise enantioselective synthesis of five active pharmaceutical ingredients.
Biki Ghosh   +5 more
wiley   +2 more sources

Macrocyclic Molecular Glues for the 14‐3‐3/ChREBP Interaction: Affinity and Cooperativity in an Inverse Relationship

open access: yesAngewandte Chemie, EarlyView.
Macrocycles are effective molecular glues to stabilize the 14‐3‐3/ChREBP interaction. Linker length modulation uncovered an inverse correlation between the macrocycle binding affinity to 14‐3‐3 and its cooperativity in 14‐3‐3/ChREBP stabilization.
Marloes A. M. Pennings   +7 more
wiley   +2 more sources

Mögliche Peierls‐Verzerrung durch die Bildung von Re2‐Dimeren in den LaNiO2‐Typ Nitriden LnReN2 (Ln = Pr, Nd)

open access: yesAngewandte Chemie, EarlyView.
Diese Studie untersucht die Hochdrucksynthese von zwei neuen Perovskit‐verwandter Nitriden mit geordneten Anionen‐Fehlstellen, PrReN2 und NdReN2, welche im verzerrten LaNiO2‐Strukturtyp kristallisieren. Röntgen‐ und Neutronenbeugung zeigen eine strukturelle Verzerrung, die durch die Dimerisierung der Re‐Ketten verursacht wird, während Berechnungen der ...
Dominik Werhahn   +6 more
wiley   +1 more source

Searching for biological processes as targets for rheumatoid arthritis targeted therapy with ANDSystem, an integrated software and information platform. [PDF]

open access: yesVavilovskii Zhurnal Genet Selektsii
Mishchenko EL   +6 more
europepmc   +1 more source

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