Results 41 to 50 of about 25,482,812 (306)

On some numerical methods for solving the 1-D Saint-Venant equations of general flow regime. Part 2: Verification and application

open access: yesVietnam Journal of Mechanics, 2003
In the Part 1 of this paper [1], some numerical methods for solving the 1-D Saint-Venant equations of general flow regime have been described. This Part of the paper presents the results of verification by various test problems, covering all of three ...
Nguyen Van Hanh   +2 more
doaj   +1 more source

Diabetes‐induced vascular calcification is associated with low pyrophosphate and its oral supplementation prevents calcification in diabetic mice

open access: yesFEBS Open Bio, EarlyView.
Induction of diabetes in three different mouse strains uniformly resulted in an increase in TNAP activity and a reduction in pyrophosphate (PPi) in the circulation. Inhibition of TNAP restored plasma PPi. Diabetes‐induced calcification in the media layer of the aorta was detected only in the Abcc6−/− strain, which is predisposed to ectopic ...
Krisztina Fülöp   +13 more
wiley   +1 more source

Seatizen Atlas: a collaborative dataset of underwater and aerial marine imagery

open access: yesScientific Data
Citizen Science initiatives have a worldwide impact on environmental research by providing data at a global scale and high resolution. Mapping marine biodiversity remains a key challenge to which citizen initiatives can contribute.
Matteo Contini   +17 more
doaj   +1 more source

Einleitung

open access: yesFolia Toruniensia, 2017
Der Text schildert die wichtigsten Änderungen in der Zeitschrift, die in den letzten Jahren zustande gekommen sind. Sie beziehen sich auf den neuen Mitverleger, auf die Erschließung der Zeitschrift in der Akademischen Zeitschriftendatenbank, den Übergang
Janusz Tandecki, Mariusz Balcerek
doaj   +1 more source

Analysis of Treacher Collins syndrome 4‐associated mutations in Schizosaccharomyces pombe

open access: yesFEBS Open Bio, EarlyView.
Fission yeast models carrying Treacher Collins syndrome type 4‐associated mutations reveal that impaired processivity of RNA polymerase I leads to defective rRNA transcription. This study highlights the essential role of a conserved arginine residue in Pol I elongation and provides mechanistic insight into the pathogenesis of ribosomopathies.
Kei Kawakami, Hiroaki Kato
wiley   +1 more source

Analyzing the effects of public interventions on reducing public gatherings in China during the COVID-19 epidemic via mobile terminals positioning data

open access: yesMathematical Biosciences and Engineering, 2020
At the beginning of 2020, the novel coronavirus disease (COVID-19) became an outbreak in China. On January 23, China raised its national public health response to the highest level.
Analyzing the effects of public interventions on reducing public gatherings in China during the COVID-19 epidemic via mobile terminals positioning data
doaj   +1 more source

ATP13A2 is involved in intracellular polyamine transport in lung epithelial cells

open access: yesFEBS Open Bio, EarlyView.
Spermidine transport in lung epithelial cells involves the polyamine transporter ATP13A2. Cell proliferation is associated with the upregulation of ATP13A2. Polyamines are present in all living cells and are implicated in various crucial cellular processes such as proliferation, apoptosis and autophagy.
Yuta Hatori   +8 more
wiley   +1 more source

How to realize your scientific potential: instructions for clinicians

open access: yesРепродуктивная эндокринология, 2019
While evidence-based medicine has become an indispensable condition not only in the work of doctors, but also in the priorities of patients, for many Ukrainian clinicians and researchers continue to be difficult access to the international scientific ...
Л. М. Самчинська   +1 more
doaj   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

open access: yesFEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj   +3 more
wiley   +1 more source

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

open access: yesFEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu   +5 more
wiley   +1 more source

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