ABSTRACT Aims This retrospective cohort study described clinical outcomes, healthcare resource utilisation (HCRU), and costs among Medicare beneficiaries with or without obesity and stratified by cardiovascular disease (CVD) risk. Materials and Methods Using Medicare FFS claims (Jan 2016–Dec 2022), beneficiaries were indexed after 12 months of ...
Jiayin Xue +9 more
wiley +1 more source
Graph-based understanding of isomeric diversity in complex dissolved organic matter. [PDF]
Liu T +10 more
europepmc +1 more source
ABSTRACT Aims An update to the NICE Type 2 diabetes (T2DM) guideline in February 2022 recommended an SGLT2 inhibitor be offered to people with cardiovascular disease (CVD) or heart failure (HF) as comorbidities and considered for people at high CVD risk. We report uptake of this guideline in England 18 months after its publication.
Patrick Muller +12 more
wiley +1 more source
Advanced Chlorine Photolysis for Carbamazepine Degradation: Tuning Radicals for Dissolved Organics. [PDF]
Osei-Appau C +8 more
europepmc +1 more source
ABSTRACT Aims Hypertension remains one of the most prevalent and consequential modifiable cardiovascular risk factors worldwide, affecting approximately 1.28 billion adults globally and nearly half of the United States population. Despite the availability of effective therapies, optimal blood pressure control is achieved in fewer than one in four ...
Matthew A. Cavender
wiley +1 more source
MATLAB-candexch algorithm-enhanced UV spectrophotometric-chemometric models for green, blue, and white determination of cinnarizine, domperidone, and carcinogenic impurity in pharmaceuticals: NQS assessment and UN-SDGs integration. [PDF]
Ghanem HN +4 more
europepmc +1 more source
Hypercortisolism: Causes, Consequences and Clinical Significance – A Review of Pathophysiology
ABSTRACT Hypercortisolism or Cushing syndrome is a heterogeneous clinical spectrum caused by chronic glucocorticoid excess, ranging from exogenous Cushing syndrome to rare endogenous aetiologies and the increasingly recognised entity of mild autonomous cortisol secretion (MACS). Physiological cortisol production is tightly regulated by the hypothalamic–
Mohamed Eldib +3 more
wiley +1 more source
Linking Targeted GC-MS Disinfection Byproduct Analysis with Nontargeted LC-HRMS Characterization of Dissolved Organic Matter to Evaluate Drinking Water Treatment Performance. [PDF]
Zafra-Navarro F +5 more
europepmc +1 more source
ABSTRACT Endogenous hypercortisolism (EHC) is an underrecognised and clinically significant contributor to hypertension, particularly resistant hypertension. Once viewed as a rare entity, EHC is now understood as a spectrum of cortisol excess associated with adverse cardiometabolic outcomes and target‐organ damage.
Omar Al Dhaybi, Deepak L. Bhatt
wiley +1 more source
Deciphering the Molecular Signatures and Optical Properties of Dissolved Organic Matter in the Aksu River (Xinjiang, China) via FT-ICR MS and 3D-EEM Spectroscopy. [PDF]
Shao F, Ablikumu A, Wang Y.
europepmc +1 more source

