Results 201 to 210 of about 55,173 (262)

Baseline Computed Tomography Coronary Angiography and Polygenic Risk Profiles in Adults With Type 2 Diabetes: A Cross‐Sectional Analysis From the VOLTAIRE Study

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims To characterise baseline clinical, anatomical, and genetic cardiovascular risk profiles in participants enrolled in the VOLTAIRE (Evaluation of Polygenic Scores and CT Imaging in Risk Factor Modification in Patients with Type 2 Diabetes) study and examine concordance across these domains. Methods This analysis included adults with T2D who
Ruofei (Trophy) Chen, Adam J. Nelson, Sophia Zoungas, Robyn A. Clark, Sean Tan, Esther F. Davis, Melissa C. Southey, Andrew Lin, Giuseppe Di Giovanni, Masashi Fujino, Jennifer Wong, Robert L. O'Reilly, Jacqueline S. Dron, Stephen J. Nicholls   +13 more
wiley   +1 more source

Hydrostatic pressure induces strong leakage of dissolved organic matter from "marine snow" particles. [PDF]

Sci Adv
Stief P, Niggemann J, Bligh M, Buck-Wiese H, Wünsch U, Steinke M, Hehemann JH, Glud RN.   +7 more
europepmc   +1 more source

Hypoglycaemia Was Not Associated With Depression, Anxiety, Diabetes Distress or Fear of Hypoglycaemia Scores in People With Type 1 or Insulin‐Treated Type 2 Diabetes in the Hypo‐METRICS Study

Diabetes, Obesity and Metabolism, EarlyView.
Aisling McCarthy, Uffe Søholm, Natalie Zaremba, François Pouwer, Allan A. Vaag, Simon Heller, Julia K. Mader, Ulrik Pedersen‐Bjergaard, Bastiaan E. de Galan, Eric Renard, Mark L. Evans, Rory J. McCrimmon, Stephanie A. Amiel, Pratik Choudhary, Patrick Divilly, Hypo‐RESOLVE Consortium   +15 more
wiley   +1 more source

Amylin Analogs: The Next Major Class of Weight Loss Therapy: A Review of Experimental Data and Early‐Phase Clinical Trials

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims The management of the disease of obesity has been transformed by incretin‐based therapies; however, additional and alternative therapeutic strategies are needed to address its biological complexity. This narrative review examines the physiology of amylin and the emerging role of amylin‐based therapies in obesity management.
Abdulhameed Alhazmi, Carel W. le Roux
wiley   +1 more source

Short- and Long-Acting Psychedelics: Structure-Activity Relationships, Pharmacology, and Implications for Neuropsychiatric Therapeutics. [PDF]

ACS Chem Neurosci
Bhat A, Zolali E, Sakib MA, Rahimian M, McMahon LR, German N, Obeng S.   +6 more
europepmc   +1 more source

Early Weight Regain After GLP‐1 Receptor Agonist Discontinuation: Mechanisms and Implications for Treatment De‐Escalation Strategies

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Glucagon‐like peptide‐1 receptor agonists (GLP‐1RAs) have transformed the pharmacological management of obesity, producing substantial and sustained weight loss during active treatment. However, discontinuation of therapy is frequently followed by significant weight regain, raising important questions regarding the durability of treatment ...
M. A. Damhof, F. H. van Bruggen, E. N. van Roon   +2 more
wiley   +1 more source

Reciprocal targeting of the unfolded protein response regulator Xbp1 and the DOM-A nucleosome remodeler in Drosophila. [PDF]

Nucleic Acids Res
Kars G, Becker PB, Apostolou Z.
europepmc   +1 more source

The Upfront Effectiveness of a 6‐Week Continuous Glucose Monitoring Intervention for Non‐Insulin‐Using Individuals With Type 2 Diabetes Is No Longer Detectable at 6–12 Months: An Observational Follow‐Up of a Randomized Trial Cohort

Diabetes, Obesity and Metabolism, EarlyView.
Jiawei Ryan Zhang, Roseanne O. Yeung, Donna P. Manca, Pratima Singh, Inga Olu‐Jordan, Tawnya Perry, Gulelala Rahim, Evan M. Hagen, Darren Lau   +8 more
wiley   +1 more source

The ocean's biological carbon pump under pressure. [PDF]

Sci Adv
Middelburg JJ.
europepmc   +1 more source

Dissolved Organic Matter in the Coastal Ocean Is Structurally More Diverse Than in Terrestrial Systems, as Shown in an Amazonian Mangrove Estuary. [PDF]

Environ Sci Technol
Mitschke N, Dittmar T, Seidel M.
europepmc   +1 more source