Results 61 to 70 of about 146,324 (250)

What drives successful verbal communication?

Frontiers in Human Neuroscience, 2013
There is a vast amount of potential mappings between behaviours and intentions in communication: a behaviour can indicate a multitude of different intentions, and the same intention can be communicated with a variety of behaviours. Humans routinely solve
Miriam eDe Boer, Ivan eToni, Roel M Willems, Roel M Willems   +3 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Networking Theories on Giftedness—What We Can Learn from Synthesizing Renzulli’s Domain General and Krutetskii’s Mathematics-Specific Theory

Education Sciences, 2016
Giftedness is an increasingly important research topic in educational sciences and mathematics education in particular. In this paper, we contribute to further theorizing mathematical giftedness through illustrating how networking processes can be ...
Maike Schindler, Benjamin Rott
doaj   +1 more source

Developmental brain dynamics of numerical and arithmetic abilities

npj Science of Learning, 2021
The development of numerical and arithmetic abilities constitutes a crucial cornerstone in our modern and educated societies. Difficulties to acquire these central skills can lead to severe consequences for an individual’s well-being and nation’s economy.
Stephan E. Vogel, Bert De Smedt
doaj   +1 more source

Free odor identification engages domain-general cognitive abilities in old adults

Chemical Senses
Abstract Naming common odors can be an exceptionally challenging task even for young and healthy individuals. Due to this difficulty, tests of cued odor identification (OID) are used instead of free odor identification in cognitive, neuropsychological, or aging research. Consequently, our understanding of the cognitive demands of free
Thomas Hörberg, Jonas K Olofsson, Rohan Raj, Erika J Laukka, Maria Larsson   +4 more
openaire   +3 more sources

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Short-term memory, attentional control and brain size in primates

Royal Society Open Science
Brain size variability in primates has been attributed to various domain-specific socio-ecological factors. A recently published large-scale study of short-term memory abilities in 41 primate species (ManyPrimates 2022 Anim. Behav. Cogn. 9, 428–516. (doi:
Carel P. van Schaik, Ivo Jacobs, Judith M. Burkart, Gabriela-Alina Sauciuc, Caroline Schuppli, Tomas Persson, Zitan Song   +6 more
doaj   +1 more source

The role of domain-general cognitive abilities and decimal labels in at-risk fourth-grade students' decimal magnitude understanding [PDF]

Learning and Individual Differences, 2017
The purpose of the study was to determine whether individual differences in at-risk 4th graders' language comprehension, nonverbal reasoning, concept formation, working memory, and use of decimal labels (i.e., place value, point, incorrect place value, incorrect fraction, or whole number) are related to their decimal magnitude understanding.
Amelia S, Malone, Abbey M, Loehr, Lynn S, Fuchs   +2 more
openaire   +2 more sources

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source