Results 101 to 110 of about 2,225,636 (373)

Navigating new norms: a systematic review of factors for the development of effective digital tools in higher education

FEBS Open Bio, EarlyView.
What factors make for an effective digital learning tool in Higher Education? This systematic review identifies elements of a digital tool that published examples reveal to be features of an engaging and impactful digital tool. A systematic literature search yielded 25 research papers for analysis.
Akmal Arzeman, Jessica Haines, Connie Pritchard, Stephen Rutherford, Nigel Francis   +4 more
wiley   +1 more source

Categorization of Unorganized Text Corpora for better Domain-Specific Language Modeling

Advances in Electrical and Electronic Engineering, 2013
This paper describes the process of categorization of unorganized text data gathered from the Internet to the in-domain and out-of-domain data for better domain-specific language modeling and speech recognition.
Jan Stas, Daniel Zlacky, Daniel Hladek, Jozef Juhar   +3 more
doaj   +1 more source

Analysis of Treacher Collins syndrome 4‐associated mutations in Schizosaccharomyces pombe

FEBS Open Bio, EarlyView.
Fission yeast models carrying Treacher Collins syndrome type 4‐associated mutations reveal that impaired processivity of RNA polymerase I leads to defective rRNA transcription. This study highlights the essential role of a conserved arginine residue in Pol I elongation and provides mechanistic insight into the pathogenesis of ribosomopathies.
Kei Kawakami, Hiroaki Kato
wiley   +1 more source

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

FEBS Open Bio, EarlyView.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig, Swanhild Lohse, Sara Elahi, Nils Hartmann, Stefanie Deckert, Shutian Si, Alexander Desuki, Anja Harder   +7 more
wiley   +1 more source

Opt: A Domain Specific Language for Non-linear Least Squares Optimization in Graphics and Imaging

, 2016
Many graphics and vision problems can be expressed as non-linear least squares optimizations of objective functions over visual data, such as images and meshes.
Bernstein, Gilbert, DeVito, Zachary, Fisher, Matthew, Hanrahan, Pat, Mara, Michael, Nießner, Matthias, Ragan-Kelley, Jonathan, Theobalt, Christian, Zollhöfer, Michael   +8 more
core   +1 more source

Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications

FEBS Open Bio, EarlyView.
This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley   +1 more source

Code Generation in Computational Neuroscience: A Review of Tools and Techniques

Frontiers in Neuroinformatics, 2018
Advances in experimental techniques and computational power allowing researchers to gather anatomical and electrophysiological data at unprecedented levels of detail have fostered the development of increasingly complex models in computational ...
Inga Blundell, Romain Brette, Thomas A. Cleland, Thomas G. Close, Daniel Coca, Andrew P. Davison, Sandra Diaz-Pier, Carlos Fernandez Musoles, Padraig Gleeson, Dan F. M. Goodman, Michael Hines, Michael W. Hopkins, Pramod Kumbhar, David R. Lester, Bóris Marin, Bóris Marin, Abigail Morrison, Abigail Morrison, Abigail Morrison, Eric Müller, Thomas Nowotny, Alexander Peyser, Dimitri Plotnikov, Dimitri Plotnikov, Paul Richmond, Andrew Rowley, Bernhard Rumpe, Marcel Stimberg, Alan B. Stokes, Adam Tomkins, Guido Trensch, Marmaduke Woodman, Jochen Martin Eppler   +32 more
doaj   +1 more source

Generating natural language descriptions of Z test cases [PDF]

, 2010
Critical software most often requires an independent validation and verification (IVV). IVV is usually performed by domain experts, who are not familiar with specific, many times formal, development technologies. In addition, model-based testing (MBT) is
Cristiá, Maximiliano, Plüss, Brian
core  

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

FEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada, Mina Iwaki, Kyosuke Hagiri, Rei Izumi, Masahiko Harata, Chihiro Horigome   +5 more
wiley   +1 more source

Sparse Automatic Differentiation for Large-Scale Computations Using Abstract Elementary Algebra

, 2015
Most numerical solvers and libraries nowadays are implemented to use mathematical models created with language-specific built-in data types (e.g. real in Fortran or double in C) and their respective elementary algebra implementations.
Klus, Stefan, Peles, Slaven
core