Results 71 to 80 of about 1,144,226 (279)

Cross-Domain Recommendation via Deep Domain Adaptation [PDF]

open access: yes, 2019
The behavior of users in certain services could be a clue that can be used to infer their preferences and may be used to make recommendations for other services they have never used. However, the cross-domain relationships between items and user consumption patterns are not simple, especially when there are few or no common users and items across ...
Kanagawa, Heishiro   +4 more
openaire   +2 more sources

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

DC-LoRA: Domain correlation low-rank adaptation for domain incremental learning

open access: yesHigh-Confidence Computing
Continual learning, characterized by the sequential acquisition of multiple tasks, has emerged as a prominent challenge in deep learning. During the process of continual learning, deep neural networks experience a phenomenon known as catastrophic ...
Lin Li   +4 more
doaj   +1 more source

Domain Adaptation for Neural Networks by Parameter Augmentation

open access: yes, 2016
We propose a simple domain adaptation method for neural networks in a supervised setting. Supervised domain adaptation is a way of improving the generalization performance on the target domain by using the source domain dataset, assuming that both of the
Hashimoto, Kazuma   +2 more
core   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Privacy-Preserving Unsupervised Domain Adaptation in Federated Setting

open access: yesIEEE Access, 2020
The training of deep neural networks relies on massive high-quality labeled data which is expensive in practice. To tackle this problem, domain adaptation is proposed to transfer knowledge from label-rich source domain to unlabeled target domain to learn
Lei Song   +3 more
doaj   +1 more source

Dynamic Distribution Adaptation Based Transfer Network for Cross Domain Bearing Fault Diagnosis

open access: yesChinese Journal of Mechanical Engineering, 2021
In machinery fault diagnosis, labeled data are always difficult or even impossible to obtain. Transfer learning can leverage related fault diagnosis knowledge from fully labeled source domain to enhance the fault diagnosis performance in sparsely labeled
Yixiao Liao   +4 more
doaj   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

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