Results 41 to 50 of about 487,842 (295)

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Optimization of direct domain decomposition methods

open access: yesComputer Assisted Methods in Engineering and Science, 2023
In this paper, the problem of parallelizing the finite element method for distributed memory computers using domain decomposition methods is addressed.
Yves Escaig, Gilbert Touzot
doaj  

Adaptive Aggregation Based Domain Decomposition Multigrid for the Lattice Wilson Dirac Operator [PDF]

open access: yes, 2014
In lattice QCD computations a substantial amount of work is spent in solving discretized versions of the Dirac equation. Conventional Krylov solvers show critical slowing down for large system sizes and physically interesting parameter regions.
Frommer, Andreas   +4 more
core   +2 more sources

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

Finite element analysis of multi-material models using a balancing domain decomposition method combined with the diagonal scaling preconditioner

open access: yesNihon Kikai Gakkai ronbunshu, 2015
Actual problems in science and industrial applications are modeled by multi-materials and large-scale unstructured mesh, and the finite element analysis has been widely used to solve such problems on the parallel computer.
Masao OGINO
doaj   +1 more source

Domain decomposition finite element/finite difference method for the conductivity reconstruction in a hyperbolic equation

open access: yes, 2015
We present domain decomposition finite element/finite difference method for the solution of hyperbolic equation. The domain decomposition is performed such that finite elements and finite differences are used in different subdomains of the computational ...
Beilina, L.
core   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

open access: yesFEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini   +2 more
wiley   +1 more source

Bearing fault diagnosis algorithm based on maximum correlated kurtosis feature mode decomposition and compound Gini index

open access: yes机车电传动, 2023
The maximum correlated kurtosis feature mode decomposition (MCKFMD) method can effectively remove redundant information and enhance fault features, but its effect is affected by the number of decomposition modes, the number of initialized filters and the
YANG Gang   +4 more
doaj  

A Recursive Variant of Schwarz Type Domain Decomposition Methods

open access: yesRatio Mathematica, 2016
In this paper a slightly different approach to the use of the domain decomposition method of the Schwarz type is proposed. Instead of the standard coarse space construction we propose to use a recursive solution on each domain.
Frantisek Bubenik, Petr Mayer
doaj   +1 more source

Large-scale wave-front reconstruction for adaptive optics systems by use of a recursive filtering algorithm [PDF]

open access: yes, 2005
We propose a new recursive filtering algorithm for wave-front reconstruction in a large-scale adaptive optics system. An embedding step is used in this recursive filtering algorithm to permit fast methods to be used for wave-front reconstruction on an ...
Britton, Matthew   +2 more
core   +1 more source

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