Results 41 to 50 of about 511,748 (344)

Large-Scale Cluster Parallel Strategy for Regularized Lattice Boltzmann Method with Sub-Grid Scale Model in Large Eddy Simulation

open access: yesApplied Sciences, 2023
As an improved method of the lattice Boltzmann method (LBM), the regularized lattice Boltzmann method (RLBM) has been widely used to simulate fluid flow. For solving high Reynolds number problems, large eddy simulation (LES) and RLBM can be combined. The
Zhixiang Liu   +4 more
doaj   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Unraveling the Molecular Mechanisms of Glioma Recurrence: A Study Integrating Single‐Cell and Spatial Transcriptomics

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Glioma recurrence severely impacts patient prognosis, with current treatments showing limited efficacy. Traditional methods struggle to analyze recurrence mechanisms due to challenges in assessing tumor heterogeneity, spatial dynamics, and gene networks.
Lei Qiu   +10 more
wiley   +1 more source

A course space construction based on local Dirichlet-to-Neumann maps [PDF]

open access: yes, 2011
Coarse-grid correction is a key ingredient of scalable domain decomposition methods. In this work we construct coarse-grid space using the low-frequency modes of the subdomain Dirichlet-to-Neumann maps and apply the obtained two-level preconditioners to ...
Dohrmann C. R.   +4 more
core   +4 more sources

Elinvar Materials: Recent Progress and Challenges

open access: yesAdvanced Engineering Materials, EarlyView.
Elinvar materials, exhibiting temperature‐invariant elastic modulus, are critical for precision instruments and emerging technologies. This article reviews recent progress in the field, with a focus on the anomalous thermoelastic behavior observed in key material systems.
Wenjie Li, Yang Ren
wiley   +1 more source

Optimization of direct domain decomposition methods

open access: yesComputer Assisted Methods in Engineering and Science, 2023
In this paper, the problem of parallelizing the finite element method for distributed memory computers using domain decomposition methods is addressed.
Yves Escaig, Gilbert Touzot
doaj  

Finite element analysis of multi-material models using a balancing domain decomposition method combined with the diagonal scaling preconditioner

open access: yesNihon Kikai Gakkai ronbunshu, 2015
Actual problems in science and industrial applications are modeled by multi-materials and large-scale unstructured mesh, and the finite element analysis has been widely used to solve such problems on the parallel computer.
Masao OGINO
doaj   +1 more source

High‐performance computing of 3D blasting wave propagation in underground rock cavern by using 4D‐LSM on TianHe‐3 prototype E class supercomputer

open access: yesDeep Underground Science and Engineering, 2022
Parallel computing assigns the computing model to different processors on different devices and implements it simultaneously. Accordingly, it has broad applications in the numerical simulation of geotechnical engineering and underground engineering, of ...
Meng Fu, Gaofeng Zhao
doaj   +1 more source

A Detection Method of Magnetic Anomaly Signal in Offshore Waters

open access: yes水下无人系统学报, 2023
Magnetic anomaly signal detection has broad application prospects in offshore defense, which is an urgent problem for realizing remote and long-term monitoring. In this paper, an underwater magnetic anomaly detection model is proposed, and wavelet domain
Defeng DU   +3 more
doaj   +1 more source

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