Results 51 to 60 of about 259,102 (312)

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Optimization Acceleration Integral Method Based on Power Spectrum Estimation

open access: yesMATEC Web of Conferences, 2018
Due to the excellent performance of the frequency domain integration method, it is widely used for acceleration integral calculations. However, the frequency-domain integration needs to select the effective integration frequency band to achieve its ...
Guo Ruijie, Ye Shengbo, Ji Yicai
doaj   +1 more source

On the integral equation of an adjoint boundary value problem of heat conduction

open access: yesҚарағанды университетінің хабаршысы. Математика сериясы, 2019
An integral equation is considered, to which a nonhomogeneous first boundary value problem with an adjoint heat conduction operator is reduced. The problem is set in an infinite plane angle, that is, a boundary of the domain moves with a constant ...
M.T. Kosmakova   +4 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Anti-interrupted Sampling Repeater Jamming Method in the Waveform Domain before Matched Filtering

open access: yesLeida xuebao
Interrupted Sampling Repeater Jamming (ISRJ) falls within the category of intrapulse coherent deception interference. ISRJ employs the principle of undersampling to engender multiple spurious target peaks on the range profile, thereby disrupting the ...
Hanning SU   +4 more
doaj   +1 more source

Integral Closures of Noetherian Integral Domains as Intersections [PDF]

open access: yesProceedings of the American Mathematical Society, 1995
Let \(A\) be a noetherian integral domain, \(\overline A\) its integral closure, and let \({\mathcal G}\) be the set of prime ideals \(P\) of \(A\) with height\((P) \leq 1\). The author provides three equivalent conditions for the equality \(\overline A = \bigcap \overline A_P\), \(P \in {\mathcal G}\). For instance, equality holds iff \(\bigcap A_P\),
openaire   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Analysis of some localized boundary-domain integral equations [PDF]

open access: yes, 2009
Some direct segregated localized boundary-domain integral equation (LBDIE) systems associated with the Dirichlet and Neumann boundary value problems (BVP) for a scalar "Laplace" PDE with variable coefficient are formulated and analysed. The parametrix is
Mikhailov, SE   +2 more
core  

Localized direct boundary–domain integro–differential formulations for scalar nonlinear boundary-value problems with variable coefficients [PDF]

open access: yes, 2005
Mixed boundary-value Problems (BVPs) for a second-order quasi-linear elliptic partial differential equation with variable coefficients dependent on the unknown solution and its gradient are considered.
Mikhailov, SE, S. E. Mikhailov
core   +1 more source

Problems with Missing Tricomi Condition and Analog of Frankl Condition for One Class of Mixed Type Equations

open access: yesMathematics
In this paper, for a mixed elliptic-hyperbolic type equation with various degeneration orders and singular coefficients, theorems of uniqueness and existence of the solution to the problem with a missing Tricomi condition on boundary characteristic and ...
Assel Makulbay   +3 more
doaj   +1 more source

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