Results 81 to 90 of about 259,102 (312)
An integral-collocation-based fictitious-domain technique for solving elliptic problems [PDF]
This paper presents a new fictitious-domain technique for numerically solving elliptic second-order partial-differential equations (PDEs) in complex geometries.
See, Howard +2 more
core +1 more source
A space-domain integral equation method accelerated with adaptive cross approximation (ACA) is presented for the fast and accurate analysis of electromagnetic (EM) scattering from multilayered metallic photonic crystal (MPC).
Jianxun Su +4 more
doaj +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Mesh-based numerical implementation of the localized boundary-domain integral equation method to a variable-coefficient Neumann problem [PDF]
An implementation of the localized boundary-domain integral-equation (LBDIE) method for the numerical solution of the Neumann boundary-value problem for a second-order linear elliptic PDE with variable coefficient is discussed.
Mikhailov, SE, Nakhova, IS
core
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
This work introduces a boundary-only integral formulation that couples the precise integration method with a parametrix-based approach to solve non-homogeneous transient heat conduction problems with space- and time-dependent coefficients.
Derese Wendimu Ayitaged +2 more
doaj +1 more source
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Distributed-memory parallelization of an explicit time-domain volume integral equation solver on Blue Gene/P [PDF]
Two distributed-memory schemes for efficiently parallelizing the explicit marching-on in-time based solution of the time domain volume integral equation on the IBM Blue Gene/P platform are presented.
Cheeseman, M, Bağcı, H, Al-Jarro, A
core

