Results 71 to 80 of about 812,194 (338)
Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA
Molecular Oncology, EarlyView.Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson +2 more
wiley +1 more source
Novel spatio-temporal attention causal convolutional neural network for multi-site PM2.5 prediction
Frontiers in Environmental ScienceMulti-site PM2.5 prediction has emerged as a crucial approach, given that the accuracy of prediction models based solely on data from a single monitoring station may be constrained. However, existing multi-site PM2.5 prediction methods predominantly rely
Yong Wang, Shuang Tian, Panxing Zhang
doaj +1 more source
Rethinking Delayed Hemodynamic Responses for fNIRS Classification
IEEE Transactions on Neural Systems and Rehabilitation Engineering, 2023 Functional near-infrared spectroscopy (fNIRS) is a non-invasive neuroimaging technology for monitoring cerebral hemodynamic responses. Enhancing fNIRS classification can improve the performance of brain–computer interfaces (BCIs).
Zenghui Wang, Jihong Fang, Jun Zhang
doaj +1 more source
A Self-attention Knowledge Domain Adaptation Network for Commercial Lithium-ion Batteries State-of-health Estimation under Shallow Cycles [PDF]
, 2023 Xin Chen +5 more
openalex +1 more source
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Molecular Oncology, EarlyView.The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués +3 more
wiley +1 more source
Zhongguo Jianchuan YanjiuObjectiveThis paper seeks to solve the problem in which directly invoking an optimization algorithm for the worst-case analysis of a three-span beam structure under multiple wheel patch loads raises the possibility of falling into the local optimal ...
xiangyun LUO +3 more
doaj +1 more source
Frontiers in Bioengineering and Biotechnology, 2023 Background: Postoperative complications following total hip arthroplasty (THA) often require revision surgery. X-rays are usually used to detect such complications, but manually identifying the location of the problem and making an accurate assessment ...
Sijia Guo +7 more
doaj +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
An Integrated Framework for Data Quality Fusion in Embedded Sensor Systems
Sensors, 2023 The advancement of embedded sensor systems allowed the monitoring of complex processes based on connected devices. As more and more data are produced by these sensor systems, and as the data are used in increasingly vital areas of applications, it is of ...
Christoph Scholl +5 more
doaj +1 more source