Results 261 to 270 of about 1,057,328 (332)
The ER's continuous tubular network is maintained by ER‐shaping proteins whose mutation or dysregulation contributes to neurodegenerative diseases. Here, we show that ER morphology sets the speed of Ca2+ store replenishment between firing events. Disrupting ER continuity slows intra‐ER Ca2+ redistribution from extracellular refill (SOCE) sites, driving
Valentina Davi +13 more
wiley +1 more source
Geometric-topological deep transfer learning for precise vessel segmentation in 3D medical volumes. [PDF]
Wu J, Wen Z, Zhou H, Sun N, Zhang Y.
europepmc +1 more source
Leveraging Artificial Intelligence and Large Language Models for Cancer Immunotherapy
Cancer immunotherapy faces challenges in predicting treatment responses and understanding resistance mechanisms. Artificial intelligence (AI) and machine learning (ML) offer powerful solutions for cancer immunotherapy in patient stratification, biomarker discovery, treatment strategy optimization, and foundation model development.
Xinchao Wu +4 more
wiley +1 more source
A Mathematical Model of Cysteine-Driven Metabolic Adaptation to Hypoxia in Ovarian Cancer. [PDF]
Rodrigues JA +4 more
europepmc +1 more source
Adult Sex Ratio as a Demographic Feedback Linking Mating Systems, Parental Care, and Evolution
Breeding systems are some of the most diverse social behavior, and our team is investigation the evolutionary causes of this diversity. This review summarises our research carried out at the University of Bath. We argue that demographic components of wild populations, especially the adult sex ratio, plays a key role driving breeding system variation ...
Tamás Székely, Oscar G. Miranda
wiley +1 more source
The future of mathematical oncology in the age of AI. [PDF]
Rockne RC +18 more
europepmc +1 more source

