Results 111 to 120 of about 4,810,145 (339)

Export of miRNAs from activated macrophages is cooperative and HuR‐dependent

FEBS Letters, EarlyView.
This study uncovers a new mechanism for miRNA export regulation in mammalian cells, driven by the RNA‐binding protein HuR. In macrophages, HuR cooperatively binds with miRNAs to export both low‐ and high‐affinity substrates, thereby influencing macrophage activation.
Syamantak Ghosh, Kamalika Mukherjee, Suvendra N. Bhattacharyya   +2 more
wiley   +1 more source

Sparse-View CT Reconstruction Based on a Hybrid Domain Model with Multi-Level Wavelet Transform. [PDF]

Sensors (Basel), 2022
Bai J, Liu Y, Yang H.
europepmc   +1 more source

A Fully Time-domain Neural Model for Subband-based Speech Synthesizer

, 2019
This paper introduces a deep neural network model for subband-based speech synthesizer. The model benefits from the short bandwidth of the subband signals to reduce the complexity of the time-domain speech generator.
Kim, Geonmin, Kim, Tae-Ho, Lee, Soo-Young, Rabiee, Azam   +3 more
core  

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

Molecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath, Irene A. George, Srikanth S. Manda, Prasanth Ariyannur, Ekta R. Dhawale, Raja Sekhar Kommu, Rajan Datar, Darshana Patil, Vinita Trivedi, Manisha Singh, Kumar Prabhash, Sewanti Limaye, Richa Chauhan, Prashant Kumar   +13 more
wiley   +1 more source

Deep Learning Multi-Domain Model Provides Accurate Detection and Grading of Mucosal Ulcers in Different Capsule Endoscopy Types. [PDF]

Diagnostics (Basel), 2022
Kratter T, Shapira N, Lev Y, Mauda O, Moshkovitz Y, Shitrit R, Konyo S, Ukashi O, Dar L, Shlomi O, Albshesh A, Soffer S, Klang E, Ben Horin S, Eliakim R, Kopylov U, Margalit Yehuda R.   +16 more
europepmc   +1 more source

Issues in Planning Domain Model Engineering [PDF]

The paper raises some issues relating to the engineering of domain models for automated planning. It studies the idea of a domain model as a formal specification of a domain, and considers properties of that specification.
McCluskey, T.L., Vallati, Mauro, Vaquero, Tiago   +2 more
core  

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

A Real-Time, GPU-Based Implementation of Aperture Domain Model Image REconstruction. [PDF]

IEEE Trans Ultrason Ferroelectr Freq Control, 2021
Khan C, Dei K, Schlunk S, Ozgun K, Byram B.   +4 more
europepmc   +1 more source

Survivin and Aurora Kinase A control cell fate decisions during mitosis

Molecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir, Shalitha Wickrama Arachchige, Sally P. Wheatley   +2 more
wiley   +1 more source

Toward a mixed reality domain model for time-Sensitive applications using IoE infrastructure and edge computing (MRIoEF). [PDF]

J Supercomput, 2022
Elawady M, Sarhan A, Alshewimy MAM.
europepmc   +1 more source