Results 151 to 160 of about 4,810,145 (339)
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
Cross-Domain Recommendation Meets Large Language Models [PDF]
Ajay Krishna Vajjala +3 more
openalex +1 more source
Erratum: Simple model for multistability and domain formation in semiconductor superlattices [PDF]
, 1995 F. Prengel, A. Wacker, Eckehard Schöll
openalex +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Adaptive bridge model for compressed domain point cloud classification
EURASIP Journal on Image and Video ProcessingThe recent adoption of deep learning-based models for the processing and coding of multimedia signals has brought noticeable gains in performance, which have established deep learning-based solutions as the uncontested state-of-the-art both for computer ...
Abdelrahman Seleem +3 more
doaj +1 more source
SecureBERT: A Domain-Specific Language Model for Cybersecurity [PDF]
, 2022 Ehsan Aghaei +3 more
openalex +1 more source
Redox regulation meets metabolism: targeting PRDX2 to prevent hepatocellular carcinoma
Molecular Oncology, EarlyView.PRDX2 acts as a central redox hub linking metabolic dysfunction‐associated steatohepatitis (MASH) to hepatocellular carcinoma (HCC). In normal hepatocytes, PRDX2 maintains redox balance and metabolic homeostasis under oxidative stress. In contrast, during malignant transformation, PRDX2 promotes oncogenic signaling, stemness, and tumor initiation ...
Naroa Goikoetxea‐Usandizaga +2 more
wiley +1 more source
Domain Modelling in Computational Persuasion for Behaviour Change in Healthcare [PDF]
, 2018 Lisa A. Chalaguine +6 more
openalex +1 more source
Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source