Results 171 to 180 of about 331,713 (291)

Rules railroad: Syntax-inspired diagrams for visualizing and understanding rule-based model specifications. [PDF]

PLoS Comput Biol
Patel RJ, Blinov ML.
europepmc   +1 more source

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

FEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel, Carlos DeOcesano Pereira, Aline Ramos Maia Lobba, Melissa Regina Fessel, Ana Marisa Chudzinski‐Tavassi   +4 more
wiley   +1 more source

Integrative phenotypic and functional genomic characterization of virulence and antimicrobial resistance in <i>Salmonella enterica</i> isolates from reptiles. [PDF]

Front Microbiol
Satharasinghe DA, Pellissery AJ, Kariyawasam S, Bommineni YR, Simon DA, Zhou L, Abramzon Y, Stanek D, Denagamage T.   +8 more
europepmc   +1 more source

MiR‐513a promotes human erythroid differentiation by modulating c‐Jun

FEBS Open Bio, EarlyView.
During early human erythropoiesis, miR‐513a promoted erythroid differentiation in primary human CD34+ hematopoietic stem‐progenitor cells and human TF‐1 erythroleukemic cells by indirectly decreasing c‐Jun and phospho‐c‐Jun expression, which are associated with increased GATA1 expression.
MinJung Kim, Brittany Taylor, Shannon Bolten, Christian L. Eberly, Mahliya Abdurahman, T. Michael Creed, Acong Yang, Taylor L. Hatchet, Tristan Dyson, Shuo Gu, Curt I. Civin, Tami J. Kingsbury   +11 more
wiley   +1 more source

VectorSage: enhancing PubMed article retrieval with advanced semantic search. [PDF]

Bioinform Adv
Wijesekara Y, Brahma R, Lotfi M, Vollmer M, Kaderali L.   +4 more
europepmc   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

Online Health Information Seeking for Pregnancy-Related Resources and Maternal eHealth Literacy Among Women in Thailand: A Qualitative Study. [PDF]

Int J Womens Health
Deeboonno A, Maneesriwongul W, Phumonsakul S, Orathai P.   +3 more
europepmc   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

Measurement and evaluation for privacy benefits of deploying encrypted DNS protocol between recursive and authoritative servers

网络与信息安全学报
The encrypted DNS protocol was originally designed to protect DNS communication privacy between users and recursive resolvers (user-recursive side). Currently, encrypted DNS communication has been widely deployed.
DUAN Liying, LI Ruixuan, LIU Ximeng, SHAO Jun, LIU Baojun   +4 more
doaj  

Simulation degradation datasets for health prognosis of a control moment gyroscope's flywheel system. [PDF]

Data Brief
Tang D, Liang S, Han D, Chen B, Yu J.
europepmc   +1 more source