Results 71 to 80 of about 1,239,786 (260)
Simulation of Indexing and Clocking with a New Multidimensional Time Harmonic Balance Approach
International Journal of Turbomachinery, Propulsion and PowerAlongside the capability to simulate rotor–stator interactions, a central aspect within the development of frequency-domain methods for turbomachinery flows is the ability of the method to accurately predict rotor–rotor and stator–stator interactions on ...
Laura Junge +3 more
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Combining Evidence Sources in Time Domain With Decision Maker’s Preference on Time Sequence
IEEE Access, 2019 Given the fusion problem of uncertain information on the time domain, this paper proposes a time-domain evidence fusion method involving the time sequence of the decision-maker based on evidence theory to give full expression to the influence of dynamic ...
Bo Zhang +3 more
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Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Komunika, 2017 Cognitive science is a science which studies how human mental processes to influence one’s behavior. Principal major issue that needs to be known in the understanding of cognitive science and their development is related to how the initial state of ...
Ellen Prima
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Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
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FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
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Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
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Influence of PAS domain flanking regions on oligomerisation and redox signalling by NifL.
PLoS ONE, 2012 Per-ARNT-Sim (PAS) domains constitute a typically dimeric, conserved α/β tertiary fold of approximately 110 amino acids that perform signalling roles in diverse proteins from all kingdoms of life.
Richard Little, Peter Slavny, Ray Dixon
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Constant domain polymorphisms influence monoclonal antibody stability and dynamics. [PDF]
Protein Sci, 2023 Warrender AK +4 more
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Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source