Results 181 to 190 of about 803,494 (308)

Calculation Method and Characteristics of Periodic Pile Arrangement Based on Artificial Spring Model

工程科学与技术
As a new type of vibration reduction system, periodic row piles achieve vibration suppression and even isolation, which is of great significance in the field of vibration isolation and damping.
GUO Wenjie, CHAI Tianjian, YAN Jianwei, ZHANG Cheng, HONG Xian   +4 more
doaj  

Virtual State Coupled Sliding Mode Control: An Energy Exchange Approach with Tunable Performance Trade-Off. [PDF]

Sensors (Basel)
Wang J, Wang J, Jing J, Zhao C, Zhang L.
europepmc   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

A Wavefield-Domain Method for Refining Residual Timing Errors in Passive-Source Seismic Exploration. [PDF]

Sensors (Basel)
Song J, Zhu G, Li Q, Zhang Y.
europepmc   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

OTFS channel estimation method based on IBO-dynamic gated Bi-GRU. [PDF]

Sci Rep
Hou J, Wei Z, Ji Y, Deng X.
europepmc   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

Topology optimization of wheel spoke cavities for lightweight design under bending fatigue and impact load cases. [PDF]

Sci Rep
Zhang G, Cui X, Zang Y, Zhou Y, Lu J, Li Z, Yang H, Wang J, Ye Z, Li R, Zhou L.   +10 more
europepmc   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Surface morphology modulation in chlorine-doped diisopropylammonium bromide film via Cl-induced domain refinement. [PDF]

iScience
Gao J, Liu X.
europepmc   +1 more source