Results 251 to 260 of about 83,637 (272)
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BCL-XL Dimerization by Three-dimensional Domain Swapping
Journal of Molecular Biology, 2006Dimeric interactions among anti- and pro-apoptotic members of the BCL-2 protein family are dynamically regulated and intimately involved in survival and death functions. We report the structure of a BCL-X(L) homodimers a 3D-domain swapped dimer (3DDS).
Jason W, O'Neill +3 more
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Domain Swapping in N-truncated Human Cystatin C
Journal of Molecular Biology, 2004Human cystatin C (HCC) inhibits papain-like cysteine proteases by a binding epitope composed of two beta-hairpin loops and the N-terminal segment. HCC is found in all body fluids and is present at a particularly high level in the cerebrospinal fluid.
Robert, Janowski +3 more
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Structure of infectious prions: stabilization by domain swapping
The FASEB Journal, 2005ABSTRACT A candidate structure for the minimal prion infectious unit is a recently discovered protein oligomer modeled as a β‐helical prion trimer (BPT); BPTs can stack to form cross‐β fibrils and may provide insight into protein aggregates of other amyloid diseases.
Sichun, Yang +3 more
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Domain swapping in the sporulation response regulator Spo0A
Journal of Molecular Biology, 2000Adaptive responses of micro-organisms, such as chemotaxis and sporulation, are governed by two-component systems consisting of sensor kinases, that interpret environmental signals, and response regulators which activate the appropriate physiological responses.
R J, Lewis +5 more
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3D domain swapping and protein aggregation
2006Bovine pancreatic ribonuclease (RNase A) has been converted to a fibrillar form by expanding, with an insertion of ten glutamines, the peptide connecting the core domain of the protein with the C-terminal b-strand [1]. The designed amyloid-like fiber of RNase A contains 3D domain swapped molecules capable of enzymatic activity, thus supporting the ...
MERLINO, ANTONELLO +4 more
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TCX: Texture and Channel Swappings for Domain Generalization
SSRN Electronic Journal, 2022Jaehyun Choi +3 more
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Faculty Opinions recommendation of 3D domain swapping: as domains continue to swap.
Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature, 2016openaire +1 more source
Protein folding and three-dimensional domain swapping: astrained relationship?
Current Opinion in Structural Biology, 2002Marcia E Newcomer
exaly