Results 91 to 100 of about 135,956 (352)

PlantGFM: A Genomic Foundation Model for Discovery and Creation of Plant Genes

Advanced Science, EarlyView.
A plant genomic foundation model pre‐trained on 12 species enables both accurate gene prediction and de novo gene design. Through AI‐human knowledge screening, seven designed sequences showed transcriptional activity in plants, with two expressing stable proteins—demonstrating the first DNA‐RNA‐protein expression of LLM‐generated genes in plants and ...
Changhao Li, Qizhe Zhang, Hanchen Chen, Kepeng Lin, Chengfang Luo, Mengying Yang, Wei Xu, Fan Yao, Jianbing Yan, Qing‐Yong Yang, Xuehai Hu   +10 more
wiley   +1 more source

Recurrent co-domestication of PIF/Harbinger transposable element proteins in insects

Mobile DNA, 2022
Background Transposable elements (TEs) are selfish DNA sequences capable of moving and amplifying at the expense of host cells. Despite this, an increasing number of studies have revealed that TE proteins are important contributors to the emergence of ...
Dragomira N. Markova, Fatema B. Ruma, Claudio Casola, Ayda Mirsalehi, Esther Betrán   +4 more
doaj   +1 more source

The Spatiotemporal Genetic Architecture of Seed Vigor in Upland Cotton

Advanced Science, EarlyView.
Leveraging the semi‐automated SeedRanger platform, we profiled the germination kinetics of 356 cotton accessions at a 30‐min interval. This high‐throughput phenomic approach delineated a temporal genetic network comprising 541 stage‐specific loci. Crucially, functional validation identified FLA2 as a pivotal, auxin‐modulated regulator that orchestrates
Luyao Wang, Jie Dai, Ting Zhao, Shengjun Zhao, Hongyu Wu, Jiaying Pan, Yupeng Hao, Ke Nie, Li Yu, Yumeng Zhu, Xiangyi Zhao, Kai Huang, Mengke Zhang, Yongyan Zhao, Yaping Jiang, Siyuan Wang, Yiling Pan, Yubing Chen, Yilai Lin, Wanghong Shi, Yayuan Deng, Jin Han, Jie Li, Xuan Long, Junbin Wang, Zhiyuan Zhang, Zegang Han, Zhanfeng Si, Lei Ju, Jun Li, Tianzhen Zhang, Ji Zhou, Xueying Guan   +32 more
wiley   +1 more source

Do dogs form reputations of humans? No effect of age after indirect and direct experience in a food-giving situation

Animal Cognition
Animals can form reputations of individuals through direct interactions or by observing interactions with a third party, known as eavesdropping. Given their cooperative relationship with humans, considerable interest has focused on whether dogs (Canis ...
Hoi-Lam Jim, Kadisha Belfiore, Eva B. Martinelli, Mayte Martínez, Friederike Range, Sarah Marshall-Pescini   +5 more
doaj   +1 more source

Personality traits in free-ranging dogs: Do experimental tests mirror natural behavior?

iScience
Summary: While animal personality research is expanding, methods used to assess personality traits of free-ranging animals are often unreliable or report mixed results in the validation process.
Urša Blenkuš, Friederike Range, Debora Prince, Corisande Abiven, Giulia Cimarelli, Sarah Marshall-Pescini   +5 more
doaj   +1 more source

Genomics Approaches to Domestication Studies of Horticultural Crops

Horticultural Plant Journal, 2019
The majority of crops we eat today are derived from the domestication of their wild progenitors. Crop domestication satisfies the human need for food and nutrition.
Zhongmin Yang, Guixiang Li, Denise Tieman, Guangtao Zhu   +3 more
doaj   +1 more source

Multi‐Targeting Carnosic Acid Kills Drug‐Resistant Helicobacter pylori With Narrow‐Spectrum Activity

Advanced Science, EarlyView.
Carnosic acid selectively eradicates drug‐resistant Helicobacter pylori through a multi‐targeted mechanism involving urease inhibition, membrane disruption, and biofilm eradication. It exhibits no detectable resistance, potent in vivo efficacy, and minimal impact on gut microbiota, positioning it as a promising narrow‐spectrum lead compound against ...
Yuefan Bai, Hongming Huang, Xudong Hang, Shanwei Hu, Qian Tong, Jingchen Xu, Jia Jia, Hongkai Bi   +7 more
wiley   +1 more source

Using archaeogenomic and computational approaches to unravel the history of local adaptation in crops [PDF]

, 2014
Our understanding of the evolution of domestication has changed radically in the past 10 years, from a relatively simplistic rapid origin scenario to a protracted complex process in which plants adapted to the human environment.
Kitchen, James, Smith, Oliver, Ware, R., Allaby, Robin G., Smith, O., Gutaker, Rafał M., Allaby, R. G., Gutaker, R., Clarke, Andrew C., Palmer, Sarah A., Kitchen, J. L., Gutaker, Rafal, Pearson, Neil, Kitchen, James L., Clarke, A. C., Ware, Roselyn, Pearson, N.   +16 more
core   +1 more source

Taming Flexibility: Synergistic Pore and Polarity Engineering in a MOF for High‐Efficiency Xe/Kr Separation

Advanced Science, EarlyView.
Through a mixed‐ligand strategy that precisely regulates pore size and framework polarity, the Xe adsorption behavior is transformed from flexible to near‐rigid. ZIF‐7‐Cl(20) achieves sensitive recognition, efficient capture, and high selectivity for Xe, enabling high‐efficiency separation from Xe/Kr mixtures.
Tao Zhao, Xue Wang, Youjin Gong, Siqi Dong, Shunshun Xiong, Hui Xu, Aziz Bakhtiyarovich Ibragimov, Thamraa Alshahrani, He Zheng, Lin Li, Junkuo Gao   +10 more
wiley   +1 more source

Fear, love, and the origins of canid domestication: An oxytocin hypothesis

Comprehensive Psychoneuroendocrinology, 2022
The process of dog domestication likely involved at least two functional stages. The initial stage occurred when subpopulations of wolves became synanthropes, benefiting from life nearby or in human environments. The second phase was characterized by the
Yury E. Herbeck, Marina Eliava, Valery Grinevich, Evan L. MacLean   +3 more
doaj   +1 more source