Results 61 to 70 of about 3,313 (297)

Delivery of Pleckstrin‐Homology Domains Suppresses PI3K/Akt Signaling and Breast Cancer Metastasis

Advanced Science, EarlyView.
Current therapies curb tumor growth but not metastasis. Obscurin, a giant metastasis suppressor lost in breast cancer, restrains PI3K/Akt signaling but is impractical to restore. We deploy a mini‐obscurin, comprising the obscurin‐PH‐domain, which sequesters PI3K‐p85, potently suppressing invasion and metastasis.
Matthew Eason, Anindya Sen, Suhan Cho, Se Jong Lee, Keyata Thompson, Md Musavvir Mahmud, Poornima Dubey, Talia Guardia, Anthony Kim, Stuart Martin, Nathan Wright, Konstantinos Konstantopoulos, Aikaterini Kontrogianni‐Konstantopoulos   +12 more
wiley   +1 more source

Epidemiology of Chagas disease in Jaguaruana, Ceará, Brazil. I. Presence of triatomines and index of Trypanosoma cruzi infection in four localities of a rural area

Memorias do Instituto Oswaldo Cruz, 2004
In order to assay the triatomine infestation and domiciliation in the rural area of Jaguaruana district, state of Ceará, Brazil, we studied, from November 2000 to April 2002, 4 localities comprising 158 domiciles as a whole, with an average of 4 ...
Otília Sarquis, José Borges-Pereira, José Roberto Mac Cord, Taís Ferreira Gomes, Pedro Hernán Cabello, Marli Maria Lima   +5 more
doaj   +1 more source

The Transcription Factor FgSge1 Harnesses the SAGA Complex to Activate Mycotoxin Biosynthesis and Fungal Virulence

Advanced Science, EarlyView.
This study reveals the molecular mechanism by which the transcription factor FgSge1 regulates mycotoxin biosynthesis and virulence in Fusarium graminearum. FgSge1 binds to the TAARGTTT cis‐element, enabling self‐activation. It recruits the SAGA complex, promotes histone acetylation, and facilitates jet‐like chromatin remodeling, thereby activating ...
Yueqi Zhang, Jingrui Wang, Qiaowan Chen, Chen Jiao, Yun Chen, Zhongshou Wu, Zhonghua Ma   +6 more
wiley   +1 more source

Studies on mosquitoes (Diptera: Culicidae) and anthropic environment: 1- Parity of blood seeking Anopheles (Kerteszia) in South-Eastern Brazil

Revista de Saúde Pública, 1993
Populations of Anopheles (Kerteszia) were sampled fortnightly over a one-year period (August 1991 to July 1992) at Ribeira Valley, S. Paulo State, Brazil. Indoor and outdoor collections were made on human bait at evening crepuscular period.
Forattini Oswaldo Paulo, Kakitani Iná, Massad Eduardo, Gomes Almério de Castro   +3 more
doaj  

Pensar con los archivos

Cuadernos LIRICO
This article proposes an archival policy based on involvement, with a constructive and critical will that takes into account the affective dimension.
Graciela Goldchluk
doaj   +1 more source

Circular RNA circNrip1 Interacts with SYNCRIP to Promote Neuropathic Pain by Stabilizing Tlr2 mRNA in Primary Sensory Neurons

Advanced Science, EarlyView.
Model of circNrip1 (cNrip1) upregulation driving neuropathic pain mechanisms. After peripheral nerve injury, increased FUS triggers the formation and upregulation of cNrip1 in injured DRG neurons. Upregulated cNrip1 recruits SYNCRIP to the 3′‐UTR of Tlr2 mRNA by binding to both, thereby promoting SYNCRIP‐triggered Tlr2 mRNA stability and increasing ...
Xiaozhou Feng, Jifang Xiao, Congcong Huang, Bao‐Chun Jiang, Bing Wang, Xu Li, Shibin Du, Tolga Berkman, Chun‐Hsien Wen, Weihua Cai, Dilip Sharma, Kun Wang, Longfei Ma, Huijuan Hu, Yuan‐Xiang Tao   +14 more
wiley   +1 more source

Epidemiologic studies of chagas' disease in the urban zone of Teresina. State of Piauí, northeastern Brazil

Revista da Sociedade Brasileira de Medicina Tropical, 1984
The triatomine species Rhodnius nasutus and Triatoma pseudomaculata were captured on palm trees Orbignya martiana "babaçu ", in the urban zone of Teresina. This kind of palm tree is largely distributed in Piauí State.
Dalva N. da C. Bento, Ana Z. C. L Branco, Marise R. Freitas, Artur da S. Pinto   +3 more
doaj   +1 more source

Allergy clinics in times of the SARS-CoV-2 pandemic: an integrated model

Clinical and Translational Allergy, 2020
Background Almost the entire World is experiencing the Coronavirus-Disease-2019 (COVID-19) pandemic, responsible, at the end of May 2020, of more than five million people infected worldwide and about 350,000 deaths. In this context, a deep reorganization
Giacomo Malipiero, Enrico Heffler, Corrado Pelaia, Francesca Puggioni, Francesca Racca, Sebastian Ferri, Lina Spinello, Morena Merigo, Donatella Lamacchia, Giuseppe Cataldo, Melissa Sansonna, Giorgio Walter Canonica, Giovanni Paoletti   +12 more
doaj   +1 more source

The European investment fund and the evidence of the undertakings for collective investment in transferable securities (UCITS) marker [PDF]

In this article we would like to analyze The European Investment Fund and the trends registered by the Undertakings for Collective Investment in Transferable Securities (UCITS) Market.
Cristina CURUTIU, Ioan TRENCA
core  

LA NAVIGATION DE PLAISANCE : UNE ACTIVITE TOURISTIQUE « AMPHIBIE » ENTRE ESPACES DE PRATIQUES ET TERRITOIRES DE GESTION [PDF]

, 2008
Since the beginning of mass tourism, pleasure boating is a particular way of territoriality through various équipment along the coastline (harbours, marinas, nautical sector firms, slipways...) and ebbing and flowing as well maritime as terrestrial ...
Sonnic, Ewan
core   +1 more source