Results 111 to 120 of about 77,989 (312)
Advanced Science, EarlyView.Endothelial GPR68 is identified as a critical regulator of collateral artery growth in peripheral artery disease. Genetic and pharmacological evidence demonstrates that GPR68 integrates hemodynamic cues to drive monocyte recruitment and inflammatory remodeling, thereby promoting collateral arteriogenesis and tissue perfusion after ischemia ...
Yiyan Song +12 more
wiley +1 more source
Advanced Science, EarlyView.Paraventricular CRF neurons in the hypothalamus project to glutamatergic neurons of the spinal trigeminal caudal nucleus, enhancing neuronal activation and CRFR2 signaling. This pathway increases CRF release and excitatory drive, promoting central sensitization and migraine‐related behaviors. Targeting the PVN–SP5C circuit provides a potential strategy
Jiang Bian +13 more
wiley +1 more source
Vestibular reactions in patients during occlusion form of chorioependymitis [PDF]
A change in intracranial pressure during chorioependymitis is discussed. The inflammatory process in the choroid plexi and walls of the cerebral ventricles is described.
Arifdzhanov, B. K., Ladyzhenskaya, E. A.
core +1 more source
A Neural Model of How the Cortical Subplate Coordinates the Laminar Development of Orientation and Ocular Dominance Maps [PDF]
, 2002 Air Force Office of Scientific Research (F49620-98-1-0108, F49620-0 1-1-0397); Defense Advanced Research Projects Agency and the Office of Naval Research (N00014-95-1-0409); National Science Foundation (IIS-97-20333); Office of Naval Research (N00014-01 ...
Grossberg, Stephen, Seitz, Aaron
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Advanced Science, EarlyView.An activity‐dependent pathway links prefrontal circuit hypoactivity to cognitive impairment. Reduced PVA–mPFC activity upregulates NEPAS, which suppresses PTX3 secretion, leading to impaired angiogenesis, myelin deficits, and memory decline. Rescue is achieved by NEPAS knockdown or chemogenetic circuit activation.
Boya Hu +11 more
wiley +1 more source
Can the Archaeology of Manual Specialization Tell Us Anything About Language Evolution? A Survey of the State of Play [PDF]
, 2009 In this review and position paper we explore the neural substrates for manual specialization and their possible connection with language and speech. We focus on two contrasting hypotheses of the origins of language and manual specialization: the language-
Steele, J, Uomini, N
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Advanced Science, EarlyView.ABSTRACT Self‐healing materials represent a paradigm shift in designing functional biomedical devices for drug delivery, tissue regeneration, and 3D bioprinting. However, their clinical translation remains limited by challenges such as insufficient mechanical strength, potential cytotoxicity from chemical modifications, and complex activation ...
Ganjun Feng +15 more
wiley +1 more source
UNERTAN SYNDROME: A CASE SERIES DEMONSTRATING HUMAN DEVOLUTION [PDF]
, 2007 A large family with six individuals exhibiting the Unertan syndrome (UTS)was identified residing in southern Turkey. All of the individuals had mental impairments and walked on all four extremities.
Karaca, Dr. Sibel +2 more
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Advanced Science, EarlyView.This study reports the development of a fully humanized bispecific T cell engager targeting IL13RA2, a tumor‐associated antigen enriched in glioblastoma. This off‐the‐shelf immunotherapy drives potent, antigen‐dependent T cell activation and tumor killing, and prolongs survival in experimental GBM and other solid tumors models without detectable off ...
Joseph T. Duffy +16 more
wiley +1 more source
Measuring the Plasticity of Social Approach: A Randomized Controlled Trial of the Effects of the PEERS Intervention on EEG Asymmetry in Adolescents with Autism Spectrum Disorders [PDF]
, 2015 This study examined whether the Program for the Education and Enrichment of Relational Skills (PEERS: Social skills for teenagers with developmental and autism spectrum disorders: The PEERS treatment manual, Routledge, New York, 2010a) affected neural ...
Brockman, Scott +8 more
core +1 more source