Results 51 to 60 of about 77,989 (312)

Value of MRI Outcomes for Preventive and Early‐Stage Trials in Spinocerebellar Ataxias 1 and 3

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To examine the value of MRI outcomes as endpoints for preventive and early‐stage trials of two polyglutamine spinocerebellar ataxias (SCAs). Methods A cohort of 100 participants (23 SCA1, 63 SCA3, median Scale for the Assessment and Rating of Ataxia (SARA) score = 5, 42% preataxic, and 14 gene‐negative controls) was scanned at 3T up ...
Thiago J. R. Rezende, Emilien Petit, Young Woo Park, Sophie Tezenas du Montcel, James M. Joers, Jonathan M. DuBois, H. Moore Arnold, Michal Povazan, Ipek Özdemir, Guita Banan, Romain Valabregue, Philipp Ehses, Jennifer Faber, Chiadi U. Onyike, Peter B. Barker, Jeremy D. Schmahmann, Eva‐Maria Ratai, Sub H. Subramony, Thomas H. Mareci, Khalaf O. Bushara, Henry Paulson, Thomas Klockgether, Alexandra Durr, Tetsuo Ashizawa, Christophe Lenglet, Gülin Öz, READISCA Investigators   +26 more
wiley   +1 more source

Time-varying synergy/redundancy dominance in the human cerebral cortex

Journal of Physics: Complexity
Recent work has emphasized the ubiquity of higher-order interactions in brain function. These interactions can be characterized as being either redundancy or synergy-dominated by applying tools from multivariate information theory. Though recent work has
Maria Pope, Thomas F Varley, Maria Grazia Puxeddu, Joshua Faskowitz, Olaf Sporns   +4 more
doaj   +1 more source

Cranial venous sinus dominance: what to expect? Analysis of 100 cerebral angiographies

Arquivos de Neuro-Psiquiatria
We report an analysis of the cranial venous sinuses circulation, emphasizing morphological and angiographic characteristics. Methods Data of 100 cerebral angiographies were retrospectively analyzed (p = 0.05).
Matheus Augusto Pinto Kitamura, Leonardo Ferraz Costa, Danilo Otávio de Araújo Silva, Laécio Leitão Batista, Maurus Marques de Almeida Holanda, Marcelo Moraes Valença   +5 more
doaj   +1 more source

Role of HLA-A in Handedness

Medicine Science, 2015
A relationship exists between cerebral dominance and right or left handedness. Left-hemisphere dominance occurs in 97% of right-handed people and in 70% of left-handed people.
Talib Muhsin, Batool Mahdi, Hayam Raouf, Hayder Hashim, Laheeb Abid, Zena Nihad   +5 more
doaj   +1 more source

Effect of motor imagery in children with unilateral cerebral palsy: fMRI study. [PDF]

PLoS ONE, 2014
BACKGROUND: Motor imagery is considered as a promising therapeutic tool for rehabilitation of motor planning problems in patients with cerebral palsy. However motor planning problems may lead to poor motor imagery ability. AIM: The aim of this functional
Eva Chinier, Sylvie N'Guyen, Grégoire Lignon, Aram Ter Minassian, Isabelle Richard, Mickaël Dinomais   +5 more
doaj   +1 more source

Bistable perception in normal aging: perceptual reversibility and its relation to cognition [PDF]

, 2017
The effects of age on the ability to resolve perceptual ambiguity are unknown, though it depends on fronto-parietal attentional networks known to change with age. We presented the bistable Necker cube to 24 middle-aged and older adults (OA; 56–78 years)
Cao, B., Cronin-Golomb, Alice, Díaz-Santos, M., Mauro, S., Neargarder, S., Yazdanbakhsh, Arash   +5 more
core  

Developmental and Epileptic Encephalopathy due to Biallelic Pathogenic Variants in PIGM

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective PIGM encodes a critical enzyme in the glycosylphosphatidylinositol (GPI)‐anchor biosynthesis pathway. While promoter‐region mutations in PIGM have been associated with a relatively mild phenotype characterized by portal vein thrombosis and absence seizures, recent evidence suggests that coding‐region mutations result in a more severe
Júlia Sala‐Coromina, Anna Marcé‐Grau, Barbara Masotto, Marta Codina, Lamia BenJemaa, Yasmina Elaribi, Mónica Martinez‐Gallo, Roger Colobran, Angel Sanchez‐Montañez, Irene Valenzuela, Yoshiko Murakami, Alfons Macaya   +11 more
wiley   +1 more source

The control loop cardiorhythm organism of girls with atopic dermatitis in Stavropol

Наука. Инновации. Технологии, 2022
At the conditions of physiological dormancy with atopic dermatitis in the reg-ulation of heart rate leading is the 3rd level of the central loop, characterized by the dominance of the sympathetic modulation performance of stress test results in ...
Olga Alekseevna Butova, Anastasia Viktorovna Chursina   +1 more
doaj  

Developmental disorders of vision [PDF]

, 2003
This review of developmental disorders of vision focuses on a few of the many disorders that disrupt visual development. Given the enormity of the human visual system in the primate brain and complexity of visual development, however, there are likely ...
Duchaine, BC, Galaburda, AM
core   +1 more source

A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling, Mark D. Parker, Sven Kerst, Richard A. Pasternack, Jacob Tondreau, Marjolein Breur, Gemma M. van Rooijen‐van Leeuwen, Davide Tonduti, Ettore Salsano, Alejandra Darling, Joanna A. E. van Wijk, Susanna Törnroth‐Horsefield, Marianna Bugiani, Petra J. W. Pouwels, Quinten Waisfisz, Marjo S. van der Knaap, Rogier Min   +16 more
wiley   +1 more source