Results 41 to 50 of about 14,392 (301)

Measuring COVID-19 Vulnerability for Northeast Brazilian Municipalities: Social, Economic, and Demographic Factors Based on Multiple Criteria and Spatial Analysis

open access: yesISPRS International Journal of Geo-Information, 2022
COVID-19 has brought several harmful consequences to the world from many perspectives, including social, economic, and well-being in addition to health issues. However, these harmful consequences vary in intensity in different regions.
Ciro José Jardim de Figueiredo   +4 more
doaj   +1 more source

The use of rough rules in the selection of topographic objects for generalizing geographical information

open access: yesPolish Cartographical Review, 2020
Selection is a key element of the cartographic generalisation process, often being its first stage. On the other hand it is a component of other generalisation operators, such as simplification.
Fiedukowicz Anna
doaj   +1 more source

Speciation Through the Lens of Population Dynamics: A Theoretical Primer on How Small and Large Populations Diverge

open access: yesPopulation Ecology, EarlyView.
Population size and dynamics fundamentally shape speciation by influencing genetic drift, founder events, and adaptive potential. Small populations may speciate rapidly due to stronger drift, whereas large populations harbor more genetic diversity, which can alter divergence trajectories. We highlight theoretical models that incorporate population size
Ryo Yamaguchi   +3 more
wiley   +1 more source

Risk assessment in tourism system using a fuzzy set and dominance-based rough set

open access: yesTechnological and Economic Development of Economy, 2016
The purpose of this study is to identify risks, discover rule base structure and the impact of risks by knowledge base system design in one of the Iran tourism destination.
Hassanali Faraji Sabokbar   +5 more
doaj   +1 more source

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

open access: yesFEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan   +2 more
wiley   +1 more source

Planning urban pavement maintenance by a new interactive multiobjective optimization approach

open access: yesEuropean Transport Research Review, 2019
Pavement maintenance is essential to prevent the deterioration of asset value and to satisfy the expectations of all stakeholders (objectives). However, the budgets are often insufficient to keep the road pavement at optimum levels. Therefore, a decision
Maria Grazia Augeri   +2 more
doaj   +1 more source

Thermostable neutral metalloprotease from Geobacillus sp. EA1 does not share thermolysin's preference for substrates with leucine at the P1′ position

open access: yesFEBS Letters, EarlyView.
Knowing how proteases recognise preferred substrates facilitates matching proteases to applications. The S1′ pocket of protease EA1 directs cleavage to the N‐terminal side of hydrophobic residues, particularly leucine. The S1′ pocket of thermolysin differs from EA's at only one position (leucine in place of phenylalanine), which decreases cleavage ...
Grant R. Broomfield   +3 more
wiley   +1 more source

Microbial exopolysaccharide production by polyextremophiles in the adaptation to multiple extremes

open access: yesFEBS Letters, EarlyView.
Polyextremophiles are microorganisms that endure multiple extreme conditions by various adaptation strategies that also include the production of exopolysaccharides (EPSs). This review provides an integrated perspective on EPS biosynthesis, function, and regulation in these organisms, emphasizing their critical role in survival and highlighting their ...
Tracey M Gloster, Ebru Toksoy Öner
wiley   +1 more source

Linked dimers of the AAA+ ATPase Msp1 reveal energetic demands and mechanistic plasticity for substrate extraction from lipid bilayers

open access: yesFEBS Letters, EarlyView.
Cells must clear mislocalized or faulty proteins from membranes to survive. The AAA+ ATPase Msp1 performs this task, but dissecting how its six subunits work together is challenging. We engineered linked dimers with varied numbers of functional subunits to reveal how Msp1 subunits cooperate and use energy to extract proteins from the lipid bilayer ...
Deepika Gaur   +5 more
wiley   +1 more source

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