Results 31 to 40 of about 24,695,904 (268)
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Smaller is better: nanobodies meet NMR
FEBS Letters, EarlyView.Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley +1 more source
, 2013 Both neutrosophic sets theory and rough sets theory are emerging as powerful tool for managing uncertainty, indeterminate, incomplete and imprecise information. In this paper we develop an hybrid structure called rough neutrosophic sets and studied their
Florentin Smarandache +7 more
core +2 more sources
The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer
Molecular Oncology, EarlyView.Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad +2 more
wiley +1 more source
Molecular Oncology, EarlyView.Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani +9 more
wiley +1 more source
International Journal of Computational Intelligence SystemsDominance-based rough set approach is the extension of classical Pawlak rough set theories and methodologies, in which the information with preference-ordered relation on the domain of attribute value is fully considered.
Lei Wang +5 more
doaj +1 more source
Evaluation of a Dominance-Based Rough Set Approach to Interface Design [PDF]
2007 Frontiers in the Convergence of Bioscience and Information Technologies, 2007 This paper explores refinements to methods used in a procedure being developed by the authors to personalize user interfaces for online shopping support tools. In the authors' original procedure, classical methods in rough set theory are used in conjunction with traditional algorithms in web usage mining. This paper will explore an alternative approach,
Timothy Maciag +3 more
openaire +1 more source
Choquet-Based Fuzzy Rough Sets [PDF]
, 2022 Fuzzy rough set theory can be used as a tool for dealing with inconsistent data when there is a gradual notion of indiscernibility between objects. It does this by providing lower and upper approximations of concepts.
Lenz, Oliver Urs +5 more
core +1 more source
Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model
FEBS Open Bio, EarlyView.This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito +7 more
wiley +1 more source
PLoS ONEQuantitative real-time PCR of phylogenetic and functional marker genes is among the most commonly used techniques to quantify the abundance of microbial taxa in environmental samples.
Zhe Du, Sebastian F Behrens
doaj +1 more source