Results 211 to 220 of about 1,362,273 (352)

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

FEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn, Barbara Seroka, Ryszard Lazny, Zenon Lotowski, Thore Rohwerder   +4 more
wiley   +1 more source

Brassinosteroids Dominate Hormonal Regulation of Plant Thermomorphogenesis via BZR1.

Current Biology, 2018
Carla Ibáñez, C. Delker, Cristina Martinez, Katharina Bürstenbinder, Philipp Janitza, Rebecca Lippmann, W. Ludwig, Hequan Sun, G. V. James, Maria Klecker, Alexandra Großjohann, Korbinian Schneeberger, S. Prat, M. Quint   +13 more
semanticscholar   +1 more source

Monocytoid dendritic cells might be a specific marker for lung involvement in dermatomyositis. [PDF]

Diagn Pathol
Knirsch J, Al-Effah M, Popper H.
europepmc   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

AIDS could dominate Russian budget by 2020

Bulletin of the World Health Organization
Robert Walgate
doaj   +1 more source

Will Medical Schools Train AI Tutors to Teach by Humiliation? [PDF]

J Eval Clin Pract
Irfan B, Sirvent RD.
europepmc   +1 more source

Identification of functional murine mitochondrial formyl peptides and their effects on myeloid‐derived suppressor cell generation

FEBS Open Bio, EarlyView.
We first identified functional murine mitochondrial N‐formyl peptides (MT‐FPs) and investigated their effects on the in vitro myeloid‐derived suppressor cell (MDSC) generation from bone marrow cells. We demonstrated that MT‐FPs acted directly on bone marrow cells to promote MDSC generation and modulated the polymorphonuclear (PMN)‐MDSC/monocyte (M ...
Miyako Ozawa, Saori Kagoshima, Akira Yamada   +2 more
wiley   +1 more source

Decisional preferences and distress among kidney transplant recipients with impaired graft function. [PDF]

Transpl Int
Osmanodja B, Spencker JJ, Ömeroğlu ÖE, Sassi Z, Eickmann S, Roller R, Burchardt A, Hahn M, Ott T, Dabrock P, Möller S, Budde K, Herrmann A.   +12 more
europepmc   +1 more source

Chameleon sequences reveal structural effects in proteins representing micelle‐like distribution of hydrophobicity

FEBS Open Bio, EarlyView.
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman, Katarzyna Stapor, Leszek Konieczny, Krzysztof Gądek, Piotr Nowakowski   +4 more
wiley   +1 more source

Why do lactobacilli dominate the human vaginal microbiota?

BJOG: an International Journal of Obstetrics and Gynaecology, 2017
S. Witkin, I. Linhares
semanticscholar   +1 more source