Results 151 to 160 of about 7,293,468 (349)

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Dominating sets and neighbor elimination-based broadcasting algorithms in wireless networks [PDF]

, 2002
Ivan Stojmenović, M. Seddigh, Joviša Žunić   +2 more
openalex   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Co-Secure Domination Number in Some Graphs

Axioms
Let G be a graph and S⊆V(G). If S is a dominating set of G, and for each vertex u∈V(G)−S, there is a neighbor of u in S, denoted by v, such that (S∖{v})∪{u} is a dominating set of G, then S is a secure dominating set (SDS) of G.
Jiatong Cui, Tianhao Li, Jiayuan Zhang, Xiaodong Chen, Liming Xiong   +4 more
doaj   +1 more source

Minimal 2-point set dominating sets of a graph

AKCE International Journal of Graphs and Combinatorics, 2017
A set is a 2-point set dominating set (2-psd set) of a graph if for any subset , there exists a non-empty subset containing at most two vertices such that the induced subgraph is connected.
Deepti Jain, Purnima Gupta, S. Arumugam
doaj   +1 more source

Message-optimal connected dominating sets in mobile ad hoc networks [PDF]

, 2002
Khaled M. Alzoubi, Peng‐Jun Wan, Ophir Frieder   +2 more
openalex   +1 more source

A guide to reactive oxygen species in tumour hypoxia: measurement and therapeutic implications

Molecular Oncology, EarlyView.
Hypoxia reshapes tumour redox landscapes by altering compartmental ROS production (mitochondria, NOX, ER, peroxisomes). Accurate interpretation requires oxygen‐contextualised measurement (live biosensors, chemical probes, EPR, LC–MS) and awareness of artefacts (reoxygenation, probe specificity).
Lina Hacker, Elysia Sarsam, Stuart J. Conway, Ester M. Hammond   +3 more
wiley   +1 more source

Extended dominating-set-based routing in ad hoc wireless networks with unidirectional links [PDF]

, 2002
Jie Wu
openalex   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

A transmission range reduction scheme for power-aware broadcasting in ad hoc networks using connected dominating sets [PDF]

, 2003
Jie Wu, Bing Wu
openalex   +1 more source