Results 41 to 50 of about 715,404 (258)
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
FEBS Letters, EarlyView.Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
Gamma-Set Domination Graphs. I: Complete Biorientations of \u3cem\u3eq-\u3c/em\u3eExtended Stars and Wounded Spider Graphs [PDF]
, 2004 The domination number of a graph G, γ(G), and the domination graph of a digraph D, dom(D) are integrated in this paper. The γ-set domination graph of the complete biorientation of a graph G, domγ(G) is created.
Factor, Kim A. S.
core +1 more source
FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Dark matter freeze-out during matter domination [PDF]
Modern Physics Letters A, 2017 We highlight the general scenario of dark matter freeze-out while the energy density of the universe is dominated by a decoupled non-relativistic species.
S. Hamdan, James Unwin
semanticscholar +1 more source
String-dominated cosmology [PDF]
Physical Review D, 1994 If string theory controls physics at the string scale, the dynamics of the early universe before the GUT era will be governed by the low-energy string equations of motion. Studying these equations for FRW spacetimes, we find that depending on the initial conditions when the stringy era starts, and on the time when it ends, there are a wide variety of ...
Goldwirth, Dalia S., Perry, Malcolm J.
openaire +3 more sources
The domination number and the least $Q$-eigenvalue [PDF]
, 2013 A vertex set $D$ of a graph $G$ is said to be a dominating set if every vertex of $V(G)\setminus D$ is adjacent to at least a vertex in $D$, and the domination number $\gamma(G)$ ($\gamma$, for short) is the minimum cardinality of all dominating sets of $
Guo, Shu-Guang +3 more
core
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Perfect Italian domination in trees
Discrete Applied Mathematics, 2019 A perfect Italian dominating function on a graph G is a function f : V ( G ) → { 0 , 1 , 2 } satisfying the condition that for every vertex u with f ( u ) = 0 , the total weight of f assigned to the neighbors of u is exactly two.
T. Haynes, Michael A. Henning
semanticscholar +1 more source
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source