Results 91 to 100 of about 9,635,811 (355)

The role of histone modifications in transcription regulation upon DNA damage

open access: yesFEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

Perfect secure domination in graphs [PDF]

open access: yesCategories and General Algebraic Structures with Applications, 2017
Let $G=(V,E)$ be a graph. A subset $S$ of $V$ is a dominating set of $G$ if every vertex in $Vsetminus  S$ is adjacent to a vertex in $S.$ A dominating set $S$ is called a secure dominating set if for each $vin Vsetminus S$ there exists $uin S$ such that
S.V. Divya Rashmi   +3 more
doaj  

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

Independent [1,2]-number versus independent domination number

open access: yesAnalele Stiintifice ale Universitatii Ovidius Constanta: Seria Matematica, 2017
A [1; 2]-set S in a graph G is a vertex subset such that every vertex not in S has at least one and at most two neighbors in it. If the additional requirement that the set be independent is added, the existence of such sets is not guaranteed in every ...
Aleid Sahar A.   +2 more
doaj   +1 more source

Graphs With Large Semipaired Domination Number

open access: yesDiscussiones Mathematicae Graph Theory, 2019
Let G be a graph with vertex set V and no isolated vertices. A sub-set S ⊆ V is a semipaired dominating set of G if every vertex in V \ S is adjacent to a vertex in S and S can be partitioned into two element subsets such that the vertices in each subset
T. Haynes, Michael A. Henning
semanticscholar   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

open access: yesFEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf   +6 more
wiley   +1 more source

Cell density–dependent nuclear‐cytoplasmic shuttling of SETDB1 integrates with Hippo signaling to regulate YAP1‐mediated transcription

open access: yesFEBS Letters, EarlyView.
At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom   +3 more
wiley   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

Domination Number and Secure Resolving Sets in Cyclic Networks

open access: yesApplied and Computational Mathematics, 2023
Basma Mohamed, Mohamed Amin
semanticscholar   +1 more source

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