Results 91 to 100 of about 10,563,621 (305)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

On the Secure Total Domination Number of Graphs

open access: yesSymmetry, 2019
A total dominating set D of a graph G is said to be a secure total dominating set if for every vertex u ∈ V ( G ) \ D , there exists a vertex v ∈ D , which is adjacent to u, such that ( D \ { v } ) ∪ { u } is a total dominating set as well.
Abel Cabrera Martínez   +2 more
semanticscholar   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

Computation of Various Domination Numbers of Rolf Nevanlinna (RNP) Collaboration Graph

open access: yesBrazilian Archives of Biology and Technology, 2017
In this paper, we compute various Domination numbers like Outer Connected Domination (OCD), Doubly Connected Domination (DCD), Fair Domination (FD), Independence Domination (ID), 2-Packing (2-P) for Rolf Nevanlinna Prize Winners's Collaboration Graph ...
Yegnanarayanan V, Logeshwary B
doaj   +1 more source

Total and Double Total Domination Number on Hexagonal Grid

open access: yesMathematics, 2019
In this paper, we determine the upper and lower bound for the total domination number and exact values and the upper bound for the double-total domination number on hexagonal grid H m , n with m hexagons in a row and n hexagons in a column.
A. Klobucar, A. Klobučar
semanticscholar   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

open access: yesFEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf   +6 more
wiley   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

Perfect secure domination in graphs [PDF]

open access: yesCategories and General Algebraic Structures with Applications, 2017
Let $G=(V,E)$ be a graph. A subset $S$ of $V$ is a dominating set of $G$ if every vertex in $Vsetminus  S$ is adjacent to a vertex in $S.$ A dominating set $S$ is called a secure dominating set if for each $vin Vsetminus S$ there exists $uin S$ such that
S.V. Divya Rashmi   +3 more
doaj  

Fair Domination Number in Cactus Graphs

open access: yesDiscussiones Mathematicae Graph Theory, 2019
For k ≥ 1, a k-fair dominating set (or just kFD-set) in a graph G is a dominating set S such that |N(v) ∩ S| = k for every vertex v ∈ V \ S. The k-fair domination number of G, denoted by fdk(G), is the minimum cardinality of a kFD-set.
Majid Hajian, N. J. Rad
semanticscholar   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

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