Results 131 to 140 of about 10,563,621 (305)
Molecular Oncology, EarlyView.To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley +1 more source
New bounds on the \(k\)-domination number and the \(k\)-tuple domination number
Applied Mathematics Letters, 2007 The \(k\)-domination number \(\gamma_k(G)\) of a graph \(G\) is the cardinality of the smallest set \(D\) of vertices of \(G\) such that every vertex \(v\in V(G)\setminus D\) has at least \(k\) neighbors in \(D\); the \(k\)-tuple domination number \(\gamma_{\times k}\) is the smallest cardinility of a set \(D\) such that every vertex \(v\) of \(G\) has
Rautenbach, Dieter, Volkmann, Lutz
openaire +2 more sources
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Upper signed domination number
Discrete Mathematics, 2008 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Tang, Huajun, Chen, Yaojun
openaire +2 more sources
Molecular Oncology, EarlyView.Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Molecular Oncology, EarlyView.Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
On the Locating Edge Domination Number of Comb Product of Graphs
, 2018 Let G = (V, E) be a graph. For e1 ∈ E, N (e1) denote the neighborhoods of e1 in G. A set D ⊆ E is a locating edge dominating set if every two distinct edges e1, e2 ∈ E(G) \ D satisfy that Ø ≠ N(e1) ∩ D ≠ N(e2) ∩ D ≠ Ø. The locating edge domination number
Dafik +5 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Co-Secure Domination in Jump Graphs for Enhanced Security
MathematicsThis study proposes a general approach to protect graphs using co-secure domination within jump graphs. In the context of graphs, a dominating set is a group of vertices that are either directly linked or connected to all other vertices within the graph.
Manjusha Pothuvath +3 more
doaj +1 more source
RIPK4 function interferes with melanoma cell adhesion and metastasis
Molecular Oncology, EarlyView.RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source