Results 141 to 150 of about 10,021,129 (363)
A note on cops and robbers, independence number, domination number and diameter [PDF]
Jan Petr, Julien Portier, Leo Versteegen
openalex +2 more sources
A linear complementarity based characterization of the weighted independence number and the independent domination number in graphs [PDF]
Parthe Pandit, Ankur A. Kulkarni
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New bounds on the \(k\)-domination number and the \(k\)-tuple domination number
The \(k\)-domination number \(\gamma_k(G)\) of a graph \(G\) is the cardinality of the smallest set \(D\) of vertices of \(G\) such that every vertex \(v\in V(G)\setminus D\) has at least \(k\) neighbors in \(D\); the \(k\)-tuple domination number \(\gamma_{\times k}\) is the smallest cardinility of a set \(D\) such that every vertex \(v\) of \(G\) has
Rautenbach, Dieter, Volkmann, Lutz
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CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir +12 more
wiley +1 more source
Upper signed domination number
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Tang, Huajun, Chen, Yaojun
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Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
On connectivity, domination number and spectral radius of the proper enhanced power graphs of finite nilpotent groups [PDF]
Sudip Bera, Hiranya Kishore Dey
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Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source

