Results 41 to 50 of about 3,356,411 (373)

Lipid Nanoparticles for the Delivery of CRISPR/Cas9 Machinery to Enable Site‐Specific Integration of CFTR and Mutation‐Agnostic Disease Rescue

open access: yesAdvanced Functional Materials, EarlyView.
Lipid nanoparticles (LNPs) are optimized to co‐deliver Cas9‐encoding messenger RNA (mRNA), a single guide RNA (sgRNA) targeting the endogenous cystic fibrosis transmembrane conductance regulator (CFTR) gene, and homologous linear double‐stranded donor DNA (ldsDNA) templates encoding CFTR.
Ruth A. Foley   +12 more
wiley   +1 more source

Evidence of Quaternary tectonics along Río Grande valley, southern Malargüe fold and thrust belt, Mendoza, Argentina [PDF]

open access: yes, 2019
The Malargüe fold and thrust belt is developed in the Argentinian Andes between 34° and 37° S, through the tectonic inversion of Upper Triassic and Lower Jurassic depocenters of the Neuquén Basin, with an uplift history since the Cretaceous.
Colavitto, Bruno   +4 more
core   +1 more source

The importance of vocabulary in language learning and how to be taught

open access: yes, 2015
Vocabulary learning is an essential part in foreign language learning as the meanings of new words are very often emphasized, whether in books or in classrooms. It is also central to language teaching and is of paramount importance to a language learner.
Mofareh Alqahtani
semanticscholar   +1 more source

Observation of the diphoton decay of the Higgs boson and measurement of its properties [PDF]

open access: yesEuropean Physical Journal C: Particles and Fields, 2014
Observation of the diphoton decay mode of the recently discovered Higgs boson and measurement of some of its properties are reported. The analysis uses the entire dataset collected by the CMS experiment in proton-proton collisions during the 2011 and ...
V. Khachatryan   +499 more
semanticscholar   +1 more source

Rational Design of Printable Carbon Nanotube Transparent Conductive Films via Data‐Driven and Mechanistic Insights

open access: yesAdvanced Functional Materials, EarlyView.
A machine learning and simulation‐guided strategy is demonstrated for gentle, non‐sonication dispersion of carbon nanotubes, preserving structural integrity and performance. This approach enables transparent conductive films with low sheet resistance, high transmittance, and sub‐20 µm printability.
Ying Zhou   +7 more
wiley   +1 more source

Don et image de don [PDF]

open access: yesIntermédialités: Histoire et théorie des arts, des lettres et des techniques, 2011
La critique filmique et la théorie du cinéma ont coutume de traiter l’expérience relationnelle entre les différents agents producteurs du film comme accessoire, relevant, au mieux, de la « petite histoire » du tournage. C’est à condition d’affranchir le film de son histoire propre que ce dernier peut faire l’objet d’une expérience esthétique supposant ...
openaire   +3 more sources

Spherical Fermatean Neutrosophic Topology [PDF]

open access: yesNeutrosophic Sets and Systems
In this paper, we introduce Spherical Fermatean Neutrosophic Topological Spaces (SFNTS), expanding on neutrosophic sets characterized by Degrees of Membership (DoM), Degrees of Indeterminacy (DoI) and Degrees of Non-Membership (DoN).
P. Roopadevi   +4 more
doaj   +1 more source

The calcareous nannofossils and magnetostratigraphic results from the Upper Tithonian-Berriasian of Feodosiya region (Eastern Crimea) [PDF]

open access: yes, 2019
This article is concerned with nannofossil study of Tithonian-Berriasian sediments of Eastern Crimea. The NJT 16, NJT 17a, NJT 17b, NKT, and NK 1 nannofossil zones were determined. The occurrence of Nannoconus kamptneri minor, one of the potential marker-
Arkadiev, V.   +4 more
core   +1 more source

Few‐Layered Conductive Graphene Foams for Electrical Transdifferentiation of Mesenchymal Stem Cells Into Schwann Cell‐Like Phenotypes

open access: yesAdvanced Healthcare Materials, EarlyView.
Few‐layered three dimansional conductive graphene foams are promising cytocompatible platforms to transdifferentiate mesenchymal stem cells into Schwann cell‐like phenotypes using electrical and microstructural cues. Applied electrical stimulation conditions resulted in activation of MAPK, neurotrphin and RAS signaling pathways that led to upregulation
Ekin G. Simsar   +9 more
wiley   +1 more source

Spatial Patterning of Modular Gelatin‐Peroxide Microspheres in Melt‐Electrowritten Scaffolds Provides Controlled Oxygen Generation and Mitigates Hypoxia and Cytotoxicity

open access: yesAdvanced Healthcare Materials, EarlyView.
A bioassembly approach is described using photo‐crosslinked gelatin‐based microgels containing calcium peroxide (CaO2) to generate oxygen (O2) and enhance cell survival in hypoxic conditions (1% O2). Bioassembly enables spatial patterning of individual CaO2‐laden and mesenchymal stem cell (MSC)‐laden microgels and allows for decoupling and mitigating ...
Axel E. Norberg   +5 more
wiley   +1 more source

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