Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
FEBS Letters, EarlyView.The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
Morphological variability of the leg muscles: potential pitfalls on ultrasound that await clinicians
Folia MorphologicaBACKGROUND: Although muscles and their tendons are not considered the most morphologically variable structures, they still manifest a substantial diversity of variants.
Marta Pośnik +4 more
doaj +1 more source
Active Decisions and Pro-social Behavior: A Field Experiment on Blood Donation [PDF]
In this paper, we propose a decision framework where people are individually asked to either actively consent or dissent to some pro-social behavior.
Alois Stutzer +2 more
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CO adsorption on (111) and (100) surfaces of the Pt sub 3 Ti alloy. Evidence for parallel binding and strong activation of CO [PDF]
, 1985 The CO adsorption on a 40 atom cluster model of the (111) surface and a 36 atom cluster model of the (100) surface of the Pt3Ti alloy was studied.
Anderson, A. B. +2 more
core +1 more source
Incongruities and Dilemmas in Data Donation: Juggling Our 1s and 0s [PDF]
, 2019 Kerina Jones
openalex +1 more source
FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
When a precedent of donation favors defection in the Prisoner's dilemma [PDF]
In this paper we examine the question of wether a collective activity can influence cooperation in a subsequent repeated one shot prisoner's dilemma (PD) game. We conduct two series of experiments.
Garapin, A., Hollard, M., Llerena, D.
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Anterior vertical mini‐incision vs. retroperitoneoscopic nephrectomy in living kidney donation: a prospective study on donors' quality of life and clinical outcome [PDF]
, 2015 Sylvia Kroencke +3 more
openalex +1 more source
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
Don't Tell Me What to Do, Tell Me Who to Follow! Field Experiment Evidence on Voluntary Donations [PDF]
We conducted a field experiment in a protected area to explore the effects of conformity to a social reference versus a comparable, but imposed, suggested donation. As observed before, we see visitors conforming to the changing social reference.
Alpizar, Francisco, Martinsson, Peter
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